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THREE PIONEERS OF CD RESEARCH: PART 1. PROF. TSUNEJI NAGAI

机译：CD研究的三个先驱：第1部分。教授。 Tsuneji Nagai

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摘要

Cyclodextrin News starts a series on the scientists having a remarkable impact on the CD research and applications. The first editorial in this series is dedicated to Prof. Tsuneji Nagai celebrating his 80th birth day on June 10. Prof. Tsuneji Nagai started his research on cyclodextrins in the seventies. His first CD-related paper was published on the interaction of a- and b-CD with several non-steroidal antiimflammatory drugs in 1975 [1]. The number of his CD-related publications is about 60. The main topics include: inclusion complex formation of NSAID drugs, barbitals, cinnarizine, carmofur, nitroglycerine, epinephrine, nasal formulation of b-interferon with DIMEB, cyclodextrin polymers for drug delivery, stabilization of photosensitive drugs via complexation, solubilization of fullerenes, preparation and characterization of large cyclodextrins and branched cyclodextrins, etc. He discovered that the drug (cinnarizine) release from its complex with bCD can be enhanced by using a competitive guest (phenylalanine) [2]. His one of the latest publication on cyclodextrins in 2010 is on fullerene solubilization with large CDs [3].
机译：Cyclodextrin News开始了一系列有关科学家对CD研究和应用产生显着影响的科学家。本系列的第一个社论是致力于Tsuneji Nagai教授，庆祝他的80岁生日。TsunejiNagai教授在七十年代开始了对Cyclodextrins的研究。他的第一篇与CD相关的论文在1975年发表了有关A和B-CD与几种非甾体类抗炎药的相互作用[1]。他与CD相关的出版物的数量约为60。主要主题包括：NSAID药物的包含复合物形成，巴比托尔，肉毒药，carmofur，Carmofur，硝酸甘油，肾上腺素，鼻甲肾上腺素，与DIMEB的Binterferon，稳定性，稳定性，稳定性的药物，药物输送，药物递送，药物递送，通过络合，富勒烯的溶解，大型环糊精和分支环糊精的大型药物的光敏药物的溶解和表征。 。他在2010年关于环糊精的最新出版物之一是与大型CD的富勒烯溶解化[3]。

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