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首页> 外文期刊>Annals of epidemiology >Body mass index and coronary heart disease risk score: the Tromso study, 1979 to 2001.
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Body mass index and coronary heart disease risk score: the Tromso study, 1979 to 2001.

机译:体重指数和冠心病风险评分:Tromso研究,1979年至2001年。

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PURPOSE: The purpose of the study is to examine the association between longitudinal change in body mass index (BMI) and change in coronary heart disease (CHD) risk score by using the Framingham risk score equation. METHODS: A general adult population in the municipality of Tromso, Norway, was invited to four consecutive examinations in 1979 to 1980, 1986 to 1987, 1994 to 1995, and 2001. A total of 10,214 men and women aged 20 to 61 years at baseline attended at least three times. Associations were examined by using fixed-effects regression methods for longitudinal data. RESULTS: We observed a significant association between BMI change and risk score change in all baseline age groups. The association was significantly strengthened by age in women, but not men. A BMI increase of 3 kg/m(2) in subjects aged 40 to 49 years was associated with risk score increases of 0.45 points (95% confidence interval [CI], 0.29-0.62) in men and 0.66 points (95% CI, 0.52-0.80) in women. CONCLUSIONS: The well-known increase in body weight is associated with adverse CHD risk in both men and women.
机译:目的:本研究的目的是通过使用Framingham风险评分方程来检查体重指数(BMI)的纵向变化与冠心病(CHD)风险评分变化之间的关联。方法:1979年至1980年,1986年至1987年,1994年至1995年和2001年,挪威特罗姆瑟市的成年人口连续接受了四次检查。基线时共有10,214名年龄在20至61岁之间的男性和女性。至少参加了三次。通过使用固定效应回归方法对纵向数据进行检查。结果:我们观察到所有基线年龄组的BMI变化与风险评分变化之间存在显着关联。女性与男性之间的关联随着年龄的增长而显着增强,而男性则没有。 40至49岁的受试者的BMI升高3 kg / m(2)与男性的风险得分增加0.45点(95%置信区间[CI],0.29-0.62)和0.66点(95%CI, 0.52-0.80)。结论:众所周知,体重增加与男性和女性冠心病的不良风险有关。

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