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首页> 外文期刊>Annals of epidemiology >A comparison of self-reported oral contraceptive use and automated pharmacy data in perimenopausal and early postmenopausal women
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A comparison of self-reported oral contraceptive use and automated pharmacy data in perimenopausal and early postmenopausal women

机译：自我报告的口服避孕药的使用和绝经后和绝经后早期妇女自动药房数据的比较

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Purpose: Oral contraceptive (OC) use can occur throughout a woman's reproductive life span with the potential for long-term impacts on health. To assess potential measurement error in prior OC use, this study compared level of agreement between self-reported prior OC use and pharmacy dispensing data in perimenopausal and/or early postmenopausal women. Methods: The study's 1399 women (ages, 45-59years) were participants in a population-based case-control study of the association between OC use and fracture risk. Episodes of lifetime self-reported OC use (in months) were collected, by telephone interview, for January 1, 2008 through November 25, 2012. Pharmacy fills, back to 1980, were collected from automated data. Agreement was measured using the prevalence-adjusted and bias-adjusted kappa index. Results: The number of women with OC pharmacy fills was 11% to 45% higher than those who reported OC use during each time period. Between-measures agreement was better for more recent use. Prevalence-adjusted and bias-adjusted kappa index values ranged from 0.88 (95% confidence interval, 0.85-0.90) within 5years from the reference date to 0.65 (95% confidence interval, 0.59-0.71) within 15 to 20years. Conclusions: For studies designed to assess the long-term effects of OC use, the current results are reassuring in noting moderate agreement between self-reported OC use and pharmacy data for up to 15 to 20years before the interview.
机译：目的：口服避孕药（OC）可能会在妇女的整个生殖寿命中发生，并可能对健康产生长期影响。为了评估先前使用OC的潜在测量误差，本研究比较了绝经前和/或绝经后早期妇女自我报告的先前OC使用与药房配药数据之间的一致性水平。方法：该研究的1399名女性（年龄在45-59岁之间）参加了基于人群的病例对照研究，研究了OC使用与骨折风险之间的关系。通过电话采访，收集了2008年1月1日至2012年11月25日终生自我报告的OC使用情节（以月为单位）。从1980年开始，自动数据收集了药房填充物。使用患病率调整和偏倚调整的卡伯指数（Kappa index）衡量一致性。结果：拥有OC药房的女性人数比每个时期报告使用OC的女性高11％至45％。措施间协议更适合于最近使用。患病率调整和偏倚调整的kappa指数值范围从参考日期开始的5年内为0.88（95％置信区间为0.85-0.90）到15至20年内的0.65（95％置信区间为0.59-0.71）。结论：对于旨在评估OC使用的长期影响的研究，当前的结果令人放心，因为可以注意到自我报告的OC使用与药房数据之间长达15至20年的适度一致。

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