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首页> 外文期刊>Annals of epidemiology >Inverse association between body mass index and chronic kidney disease in older diabetic adults
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Inverse association between body mass index and chronic kidney disease in older diabetic adults

机译：体重指数与老年糖尿病成年人的慢性肾脏疾病呈负相关

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Purpose: To identify associations among body mass index (BMI), diabetes, and chronic kidney disease (CKD) in older adults in Taiwan. Methods: This study enrolled 3334 participants aged 65 years and above who underwent an annual health screening at a medical center from January 2006 to December 2010. CKD was defined as an estimated glomerular filtration rate less than 60 mL/min/1.73 m2. A multiple logistic regression analysis was used to determine associations among BMI, diabetes, and CKD. Results: The prevalence rate of CKD was 19.7% and 10.5% in diabetic and nondiabetic subjects, respectively. A multivariate model indicated that age, diabetes, hypertriglyceridemia, low levels of high-density lipoprotein cholesterol, and hyperuricemia were associated with an increased risk of CKD. Furthermore, there was an inverse association between BMI and CKD in older diabetic patients, with odds ratios of 3.71, 2.32, 2.12, and 1.31 in underweight, normal, overweight, and obese subjects, respectively, compared with nondiabetic subjects of normal weight. Conclusions: There was an inverse association between BMI and CKD in older diabetic patients but no such association was found in nondiabetic older adults. More attention should be given to older underweight diabetic patients because they have a higher risk of CKD.
机译：目的：确定台湾老年人的体重指数（BMI），糖尿病和慢性肾脏病（CKD）之间的关联。方法：本研究招募了3334名65岁及以上的参与者，他们于2006年1月至2010年12月在医疗中心进行了年度健康筛查。CKD的定义为肾小球滤过率估计低于60 mL / min / 1.73 m2。使用多元逻辑回归分析确定BMI，糖尿病和CKD之间的关联。结果：在糖尿病和非糖尿病患者中，CKD的患病率分别为19.7％和10.5％。多元模型表明年龄，糖尿病，高甘油三酯血症，高密度脂蛋白胆固醇水平低和高尿酸血症与CKD风险增加有关。此外，老年糖尿病患者的BMI与CKD呈负相关，与正常体重的非糖尿病受试者相比，体重不足，正常，超重和肥胖受试者的比值比分别为3.71、2.32、2.12和1.31。结论：老年糖尿病患者的BMI与CKD呈负相关，而非糖尿病老年人则无此相关。体重过轻的老年糖尿病患者应给予更多关注，因为他们患有CKD的风险较高。

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