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Sleep duration and all-cause mortality: A critical review of measurement and associations

机译：睡眠时间和全因死亡率：对测量和关联的严格审查

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摘要

Purpose: Variation in sleep duration has been linked with mortality risk. The purpose of this review is to provide an updated evaluation of the literature on sleep duration and mortality, including a critical examination of sleep duration measurement and an examination of correlates of self-reported sleep duration. Methods: We conducted a systematic search of studies reporting associations between sleep duration and all-cause mortality and extracted the sleep duration measure and the measure(s) of association. Results: We identified 42 prospective studies of sleep duration and mortality drawing on 35 distinct study populations worldwide. Unlike previous reviews, we find that the published literature does not support a consistent finding of an association between self-reported sleep duration and mortality. Most studies have employed survey measures of sleep duration, which are not highly correlated with estimates based on physiologic measures. Conclusions: Despite a large body of literature, it is premature to conclude, as previous reviews have, that a robust, U-shaped association between sleep duration and mortality risk exists across populations. Careful attention must be paid to measurement, response bias, confounding, and reverse causation in the interpretation of associations between sleep duration and mortality.
机译：目的：睡眠时间的变化与死亡风险有关。这篇综述的目的是提供有关睡眠时间和死亡率的文献的最新评估，包括对睡眠时间测量的严格检查和对自我报告的睡眠时间的相关性的检查。方法：我们对报告睡眠时间与全因死亡率之间的关联性的研究进行了系统搜索，并提取了睡眠时间量度和关联度。结果：我们从全球35个不同的研究人群中鉴定了42项睡眠时间和死亡率的前瞻性研究。与以前的评论不同，我们发现已发表的文献并不支持对自我报告的睡眠持续时间与死亡率之间关联的一致发现。大多数研究采用了睡眠时间的调查指标，这些指标与基于生理指标的估计值没有高度相关性。结论：尽管有大量文献，如先前的评论所述，现在断定在整个人群中存在睡眠持续时间和死亡风险之间呈稳固的U型联系尚为时过早。在解释睡眠时间与死亡率之间的关联时，必须格外注意测量，反应偏倚，混淆和反向因果关系。

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