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首页> 外文期刊>Annals of epidemiology >Depressed mood and cause-specific mortality: A 40-year general community assessment
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Depressed mood and cause-specific mortality: A 40-year general community assessment

机译：情绪低落和特定病因死亡率：40年的一般社区评估

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Purpose: The current study describes how the excess mortality risk associated with depression translates into specific causes of death occurring during a 40-year follow-up period, with focus on deaths related to injuries, cardiovascular diseases, and cancer. Methods: Data come from a cross-sectional survey (Community Mental Health Epidemiology Study) conducted in the early 1970s in Washington County, Maryland. Random sampling for the survey resulted in 2762 interviews. For the current analyses, baseline depressed mood was linked to current participant vital status through the use of death certificates. Results: The relative subdistribution hazards for cardiovascular deaths (3.08 [1.74-5.45]) and fatal injuries (4.63 [1.76-12.18]) were significant during the entire 40-year period for young adults (18-39 years old at baseline). The relative subdistribution hazard for cardiovascular deaths during the first 15 years of follow-up was pronounced in elderly (≥65 years) males (2.99 [1.67-5.37]) subjects. There were no significant associations between depressed mood and cancer deaths. Conclusions: Individuals in the general community with depressed mood may be at increased risk of deaths as the result of cardiovascular disease and injury, even several decades after exposure assessment. Young adults with depressed mood appear to be particularly vulnerable to these associations.
机译：目的：本研究描述了与抑郁相关的额外死亡风险如何转化为在40年随访期内发生的特定死亡原因，重点是与伤害，心血管疾病和癌症相关的死亡。方法：数据来自1970年代初在马里兰州华盛顿县进行的横断面调查（社区心理健康流行病学研究）。随机抽样调查产生了2762个访谈。对于当前的分析，通过使用死亡证明将基线情绪低落与当前参与者的生命状态相关联。结果：年轻人的整个40年期间（基线时为18-39岁）的心血管死亡（3.08 [1.74-5.45]）和致命伤害（4.63 [1.76-12.18]）的相对子分布危害显着。在老年（≥65岁）男性（2.99 [1.67-5.37]）受试者中，随访的前15年中心血管死亡的相对亚分布危险明显。情绪低落与癌症死亡之间没有显着关联。结论：即使在暴露评估后的几十年中，情绪低落的普通人群也可能因心血管疾病和伤害而增加死亡的风险。情绪低落的年轻人似乎特别容易受到这些联想的影响。

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