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首页> 外文期刊>ANZ journal of surgery >Application of prognostic scoring systems in differentiated thyroid carcinoma.
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Application of prognostic scoring systems in differentiated thyroid carcinoma.

机译：预后评分系统在分化型甲状腺癌中的应用。

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BACKGROUND: Total thyroidectomy is widely practised in Australasia for papillary and follicular thyroid carcinoma. Data from large overseas series have demonstrated that patients with these cancers may be separated into risk groups based on clinicopathological prognostic factors. Furthermore, evidence suggests that low-risk patients may be safely treated with less than total thyroidectomy. The aim of the present paper was to determine what proportion of our patients with papillary and follicular thyroid cancer were in the low-risk group in order to select candidates for less aggressive treatment. METHODS: A prospectively documented series of 175 previously untreated patients with papillary and follicular thyroid carcinoma, treated principally by total thyroidectomy over a 10-year period, was divided into risk groups using the Mayo Clinic, Lahey Clinic and Memorial Hospital prognostic scoring systems. Complication rates for 103 patients treated by total thyroidectomy were also studied and reported. RESULTS: Women outnumbered men by 2.3:1. There were 128 papillary carcinomas (73%) and 47 follicular cancers (27%). These tumours were < 4 cm in diameter in 81% of patients, and 41% of patients were 40 years of age or younger. Low-risk patients accounted for 75, 81 and 45% of the study group, respectively, when the three prognostic scoring systems were applied to our patient population. The rates for recurrent laryngeal nerve palsy and permanent hypoparathyroidism for patients having total thyroidectomy were 1 and 1.9%, respectively. In the low-risk group there were no permanent complications. CONCLUSION: Most patients treated at Royal Prince Alfred Hospital during the past 10 years were low-risk patients who may have been eligible for less aggressive surgical treatment.
机译：背景：全甲状腺切除术在澳大利亚广泛用于乳头状和滤泡性甲状腺癌。海外大型研究的数据表明，根据临床病理预后因素，可以将这些癌症患者分为危险组。此外，有证据表明，对低危患者的甲状腺切除术可比全甲状腺切除术少。本文的目的是确定低危人群中乳头状和滤泡性甲状腺癌患者的比例，以便选择较不积极的治疗方案。方法：采用Mayo诊所，Lahey诊所和纪念医院的预后评分系统，将前瞻性记录的175例先前未接受治疗的乳头状和滤泡性甲状腺癌患者（主要通过全甲状腺切除术治疗10年）分为一系列风险组。还研究并报道了103例经全甲状腺切除术治疗的患者的并发症发生率。结果：女性比男性多2.3：1。有128例乳头状癌（73％）和47例滤泡状癌（27％）。在81％的患者中，这些肿瘤的直径<4 cm，年龄在40岁以下的患者占41％。当将三种预后评分系统应用于我们的患者人群时，低风险患者分别占研究组的75、81和45％。全甲状腺切除术患者的喉返神经麻痹和永久性甲状旁腺功能低下的发生率分别为1％和1.9％。在低风险组中没有永久性并发症。结论：过去10年在皇家阿尔弗雷德医院接受治疗的大多数患者均为低危患者，他们可能有资格接受不太积极的手术治疗。

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