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首页> 外文期刊>Angiology: the Journal of Vascular Diseases >No-reflow phenomenon: Pathophysiology, diagnosis, prevention, and treatment. a review of the current literature and future perspectives
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No-reflow phenomenon: Pathophysiology, diagnosis, prevention, and treatment. a review of the current literature and future perspectives

机译：无回流现象：病理生理学，诊断，预防和治疗。对当前文献和未来观点的回顾

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摘要

No-reflow is responsible for 40% of the primary percutaneous coronary intervention without complete myocardial reperfusion despite successful reopening of the infarct-related artery. This review describes the main pathophysiological mechanisms of no-reflow, its clinical manifestation, including the strong association with increased in-hospital mortality, malignant arrhythmias, and cardiac failure as well as the diagnostic methods. The latter ranges from simple angiographic thrombolysis in myocardial infarction grade score to more complex angiographic indexes, imaging techniques such as myocardial contrast echo or cardiac magnetic resonance, and surrogate clinical end points such as ST-segment resolution. This review also summarizes the strategies of prevention and treatment of no-reflow, considering the most recent studies results regarding medical therapy and devices.
机译：尽管成功重新开放了梗塞相关动脉，但无再流占40％的主要经皮冠状动脉介入治疗没有完全心肌再灌注。这篇综述描述了不复流的主要病理生理机制，其临床表现，包括与院内死亡率增加，恶性心律不齐和心力衰竭的密切相关以及诊断方法。后者的范围从心肌梗塞分级评分中的简单血管造影溶栓到更复杂的血管造影指标，成像技术（例如心肌对比回波或心脏磁共振）以及替代临床终点（例如ST段分辨率）。考虑到有关药物治疗和设备的最新研究结果，本综述还总结了预防和预防无回流的策略。

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