An automated synthesis module for preparation of L-3-(123I)iodo-alpha-methyl tyrosine.

Luurtsema G; Jager PL; Piers A; de-Hooge MN

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An automated synthesis module for preparation of L-3-(123I)iodo-alpha-methyl tyrosine.

机译：用于制备L-3-（123I）碘-α-甲基酪氨酸的自动化合成模块。

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摘要

L-3-[123I]iodo-alpha-methyl tyrosine (IMT) is an artificial amino acid suitable for SPECT imaging of various tumours. Manual synthesis of this radiopharmaceutical is reliable, but time-consuming and may require handling of large quantities of radioactivity. We developed an automated IMT synthesis module, which prepares a ready-to-inject product that meets radiopharmaceutical requirements and is identical to the manually synthesised equivalent. Current advantages include decreased operator assistance time and reduced radiation exposure. Application may be extended to other radiopharmaceuticals, including high-dose preparations for therapeutic use.

机译：L-3- [123I]碘-α-甲基酪氨酸（IMT）是适用于各种肿瘤的SPECT成像的人工氨基酸。手动合成这种放射性药物是可靠的，但是很费时，并且可能需要处理大量的放射性。我们开发了一个自动化的IMT合成模块，该模块可制备符合放射性药物要求并且与人工合成的等同物相同的即用型产品。当前的优势包括减少操作员协助时间和减少辐射暴露。应用可能会扩展到其他放射性药物，包括用于治疗用途的高剂量制剂。

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《Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine》 |2001年第6期|共6页
作者
Luurtsema G; Jager PL; Piers A; de-Hooge MN;
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正文语种 eng
中图分类原子核物理学、高能物理学;放射医学;
关键词
Methyltyrosines; Radiopharmaceuticals; 甲基酪氨酸类; 放射性药物;

机译：Methyltyrosines;Radiopharmaceuticals;甲基酪氨酸类;放射性药物;

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1. An automated synthesis module for preparation of L-3-(123I)iodo-alpha-methyl tyrosine. [J] . Luurtsema G, Jager PL, Piers A, Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine . 2001,第6期

机译：用于制备L-3-（123I）碘-α-甲基酪氨酸的自动化合成模块。
2. A Fully Automated Radiosynthesis of [~(18)F]Fluoroethyl-Diprenorphine on a Single Module by Use of SPE Cartridges for Preparation of High Quality 2-[~(18)F]Fluoroethyl Tosylate [J] . Bent W. Schoultz, Brian J. Reed, János Marton Molecules . 2013,第6期

机译：通过使用SPE弹药筒在单个模块上全自动放射性合成[〜（18）F]氟乙基-二丙诺啡，制备高质量的2- [〜（（18）F] Fluroroethyl Tosylate
3. A Fully Automated Radiosynthesis of [18F]Fluoroethyl-Diprenorphine on a Single Module by Use of SPE Cartridges for Preparation of High Quality 2-[18F]Fluoroethyl Tosylate [J] . Bent W. Schoultz, Brian J. Reed, Frode Willoch, Molecules . 2013,第6期

机译：使用SPE弹药筒在单个模块上全自动放射合成[ 18 F]氟乙基-二丙诺啡，制备高质量的2-[ 18 F]氟乙基甲苯磺酸酯
4. Automated Integration of High-Level Synthesis FPGA Modules with ROS2 Systems [C] . Daniel Pinheiro Leal, Midori Sugaya, Hideharu Amano, International Conference on Field-Programmable Technology . 2020

机译：使用ROS2系统自动集成高级合成FPGA模块
5. THE DESIGN, IMPLEMENTATION, AND ANALYSIS OF AN AUTOMATED LOGIC SYNTHESIS AND MODULE SELECTION SYSTEM [D] . LEIVE, GARY WAYNE 1981

机译：自动化逻辑综合与模块选择系统的设计，实现与分析
6. A Fully Automated Radiosynthesis of 18FFluoroethyl-Diprenorphine on a Single Module by Use of SPE Cartridges for Preparation of High Quality 2-18FFluoroethyl Tosylate [O] . Bent W. Schoultz, Brian J. Reed, János Marton, 2013

机译：使用SPE弹药筒在单个模块上全自动放射合成18F氟乙基-二丙诺啡制备高质量的2- 18F氟乙基甲苯磺酸酯
7. Evaluation of an Automated Module Synthesis and a Sterile Cold Kit–Based Preparation of 68Ga-PSMA-11 in Patients with Prostate Cancer [O] . Letizia Calderoni, Andrea Farolfi, Davide Pianori, 2019

机译：评价患有前列腺癌患者68gA-PSMA-11的自动模块合成和基于无菌的冷病试剂盒的制备
8. Automated Synthesis of Digital Hardware Modules: Simulation and Verification of Interconnections. [R] . Parker, A. C. 1983

机译：数字硬件模块的自动综合：互连的仿真和验证。

An automated synthesis module for preparation of L-3-(123I)iodo-alpha-methyl tyrosine.

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