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首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >Radioactive byproducts in (18O)H2O used to produce 18F for (18F)FDG synthesis.
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Radioactive byproducts in (18O)H2O used to produce 18F for (18F)FDG synthesis.

机译：（18O）H2O中的放射性副产物，用于为（18F）FDG合成生产18F。

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摘要

Potential radioactive byproducts in [(18)O]H(2)O irradiated with 9.6 MeV protons to produce (18)F were analyzed theoretically and experimentally. Twenty two nuclear reaction cross sections included in the National Nuclear Data Center's (NNDC) data base were selected from the possible nuclear reactions between 9.6 MeV protons and a silver havar target. Ten radionuclides: (52)Mn, (55)Fe, (55)Co, (56)Co, (57)Co, (58)Co, (59)Ni, (95)Tc, (96)Tc and (109)Cd were detected experimentally in [(18)O]H(2)O by using high purity germanium semiconductor detectors. The activities of the 10 radionuclides were distributed between 4B q and 1.2k Bq. These activities were less than the reference values given in the International Basic Safety Standards. The radionuclides derived from nuclear reactions between a silver target body and 9.6 MeV protons at a beam current 25 microA for 60 min irradiation would be exempt from restrictions for radioactive waste. The purified [(18)F]FDG prepared from (18)F produced by irradiating a silver havlar target with 9.6 MeV protons was not contaminated by the radionuclides.
机译：从理论和实验上分析了[（18）O] H（2）O中用9.6 MeV质子辐照产生（18）F的潜在放射性副产物。国家核数据中心（NNDC）数据库中包含的22个核反应截面是从9.6 MeV质子和一个哈弗银靶之间可能发生的核反应中选择的。十种放射性核素：（52）Mn，（55）Fe，（55）Co，（56）Co，（57）Co，（58）Co，（59）Ni，（95）Tc，（96）Tc和（109）使用高纯度锗半导体探测器在[（18）O] H（2）O中实验检测了Cd。 10种放射性核素的活性分布在4B q和1.2k Bq之间。这些活动小于国际基本安全标准中给出的参考值。银靶体与9.6 MeV质子在25 µA的束流下辐照60分钟产生的核反应产生的放射性核素不受放射性废物的限制。由（18）F制备的纯化的[（18）F] FDG没有被放射性核素污染，该（18）F是通过用9.6MeV质子辐照银盐靶而生产的。

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