Vitamin B2 (riboflavin) and a mixture of vitamin B2 and C affects MMC efficiency in aerated media under irradiation.

Fuga L; Kragl M; Getoff N

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Vitamin B2 (riboflavin) and a mixture of vitamin B2 and C affects MMC efficiency in aerated media under irradiation.

机译：维生素B2（核黄素）以及维生素B2和C的混合物会影响加气介质在辐照下的MMC效率。

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Vitamin B2 (Riboflavin) acts as a strong radiation protecting agent in Escherichia coli bacteria (AB1157) in aerated media. This ability is reinforced by the addition of vitamin C. Under the influence of gamma-radiation, vitamin B2 completely suppresses the cytostatic activity of mitomycin C (MMC). In the presence of both vitamins, B2 and C, MMC is converted from an efficient cytostatic to a rather strong radiation protecting agent. This effect opens a new pathway for specific protection of normal mammalian cells (with a high O2-content) under treatment with ionizing radiation.

机译：维生素B2（核黄素）在充气培养基中的大肠杆菌（AB1157）中充当强辐射防护剂。添加维生素C可以增强这种能力。在伽马射线辐射的影响下，维生素B2完全抑制丝裂霉素C（MMC）的细胞抑制活性。在两种维生素B2和C的存在下，MMC从有效的细胞抑制剂转变为相当强的辐射防护剂。这种作用为电离辐射治疗下的正常哺乳动物细胞（O2含量高）的特异性保护开辟了一条新途径。

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《Anticancer Research: International Journal of Cancer Research and Treatment》 |2004年第6期|共4页
作者
Fuga L; Kragl M; Getoff N;
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正文语种 eng
中图分类肿瘤学;
关键词
Riboflavin; Mitomycin; Radiation; Carbon ion; protect; 核黄素; 辐射;

机译：Riboflavin;Mitomycin;Radiation;Carbon ion;protect;核黄素;辐射;

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1. Vitamin B2 (riboflavin) and a mixture of vitamin B2 and C affects MMC efficiency in aerated media under irradiation. [J] . Fuga L, Kragl M, Getoff N Anticancer Research: International Journal of Cancer Research and Treatment . 2004,第6期

机译：维生素B2（核黄素）以及维生素B2和C的混合物会影响加气介质在辐照下的MMC效率。
2. Fabrication of a biodegradable polysaccharide hydrogel with riboflavin, vitamin B2, as a photo-initiator and L-arginine as coinitiator upon UV irradiation. [J] . Kim SH, Chu CC Journal of biomedical materials research. Part B, Applied biomaterials. . 2009,第1期

机译：在紫外线照射下，以核黄素，维生素B2作为光引发剂和L-精氨酸作为共引发剂，制备可生物降解的多糖水凝胶。
3. Synthesis, characterization, thermal and antimicrobial studies of diabetic drug models: Complexes of vanadyl(II) sulfate with ascorbic acid (vitamin C), riboflavin (vitamin B2) and nicotinamide (vitamin B3) [J] . Refat MS Journal of Molecular Structure . 2010,第1a3期

机译：糖尿病药物模型的合成，表征，热学和抗菌研究：硫酸氧钒（II）与抗坏血酸（维生素C），核黄素（维生素B2）和烟酰胺（维生素B3）的复合物
4. Biosensor for Detection of Vitamin B2 Based on the Voltammetric Behaviorof Vitamin B2 at a Self-Assembled Monolayer [C] . Qijin Wan International seminar on electroanalytical chemistry . 2001

机译：基于自组装单层的维生素B2的伏安行为检测生物传感器，用于检测维生素B2
5. Characterization of the endocytic pathways regulating riboflavin (vitamin B2) absorption and trafficking in human epithelial cells. [D] . Foraker, Amy B. 2007

机译：调节人上皮细胞中核黄素（维生素B2）吸收和运输的内吞途径的特征。
6. Safety and efficacy of feed additives consisting of Vitamin B2 (98) and Vitamin B2 (80) as riboflavin produced by Bacillus subtilis KCCM 10445 for all animal species (Hubei Guangji Pharmaceutical Co. Ltd.) [O] . Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, 2021

机译：饲料添加剂的安全性和有效性由维生素B2（98％）和维生素B2（80％）作为由枯草芽孢杆菌KCCM 10445为所有动物物种生产的核黄素（湖北广吉药业有限公司）
7. Determinação espectrofotométrica de vitamina B2 (riboflavina) em formulações farmacêuticas empregando sistema de análises por injeção em fluxo Spectrophotometric determination of vitamin B2 (riboflavin) in pharmaceutical formulations using flow injection analysis [O] . Clezio Aniceto, Larissa de Souza Canaes, Orlando Fatibello-Filho, 2000

机译：使用流动注射分析系统分光光度法测定药物制剂中的维生素B2（核黄素）

Vitamin B2 (riboflavin) and a mixture of vitamin B2 and C affects MMC efficiency in aerated media under irradiation.

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