...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >A case of esophageal cancer with multiple lymph node metastases which responded to neoadjuvant chemotherapy (DCF therapy).
【24h】

A case of esophageal cancer with multiple lymph node metastases which responded to neoadjuvant chemotherapy (DCF therapy).

机译：食管癌多发淋巴结转移，对新辅助化疗（DCF治疗）有反应。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It is difficult to perform radical surgery for esophageal cancer with multiple lymph node metastases. Therefore, effective neoadjuvant adjuvant treatment is necessary to achieve successful radical resection. The use of neoadjuvant chemotherapy of docetaxel, cisplatin (CDOP) and 5-fluorouracil (5-FU) (DCF) in an advanced case is reported. The patient (a 67-year-old female) was diagnosed with esophageal cancer, T3, N4, M0, stage IVa with a large number of lymph node metastases in the mediastinum and in the abdominal cavity. Neoadjuvant DCF chemotherapy was initiated in August 2006. Adverse events were mild. A complete response of the lymph node metastases in the abdominal cavity and a partial response of the esophageal lesion were achieved. The surgical procedure included a right thoracolaparotomy followed by a subtotal excision of the esophagus and two-field lymph node dissection. The cancer was diagnosed to be moderately differentiated squamous cell cancer, pT2, pN4(3c) and pstage IVa. The histological efficacy of the chemotherapy was determined to be grade 1a. Two additional courses of DCF therapy were administered followed by postoperative adjuvant chemotherapy.
机译：食管癌多发淋巴结转移很难进行根治性手术。因此，有效的新辅助治疗是成功完成根治性切除术所必需的。据报道，在晚期病例中使用多西他赛，顺铂（CDOP）和5-氟尿嘧啶（5-FU）（DCF）的新辅助化疗。该患者（一名67岁女性）被诊断患有食管癌，T3，N4，M0，IVa期，纵隔和腹腔中有大量淋巴结转移。新辅助DCF化疗于2006年8月开始。不良事件轻微。实现了腹腔淋巴结转移的完全缓解和食道病变的部分缓解。外科手术包括右胸腔镜切开术，然后将食管小计切除和两视野淋巴结清扫术。该癌症被诊断为中度分化的鳞状细胞癌，pT2，pN4（3c）和pstage IVa。化疗的组织学疗效确定为1a级。进行了另外两个疗程的DCF治疗，然后进行了辅助化疗。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号