...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Prognostic value of circulating sialyl Tn antigen in colorectal cancer patients.
【24h】

Prognostic value of circulating sialyl Tn antigen in colorectal cancer patients.

机译：循环唾液酸化Tn抗原在结直肠癌患者中的预后价值。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

To examine the prognostic value of assessing the concentration of circulating sialyl Tn antigen (STN) after surgery, we determined serum STN levels in peripheral venous blood (designated "p-") in 308 colorectal cancer patients and what we have termed the "d-p gradient" (obtained by subtracting the serum concentration in peripheral venous blood from that in the tumor's drainage venous blood) in 144 patients. The prognostic value of STN and carcinoembryonic antigen (CEA) was compared. Patients were divided into low or high p-antigen groups and low, intermediate, or high d-p gradient groups. Univariate and multivariate analyses revealed that high STN d-p gradient, high p-CEA, or high CEA d-p gradient were each independent variables for poor patient outcome after surgery, separate from stage. In conclusion, a high STN d-p gradient was a predictor of poor outcome after resection for colorectal cancer, while p-STN was not independent of stage.
机译：为了检查评估术后循环唾液酸唾液酸Tn抗原（STN）浓度的预后价值，我们确定了308名大肠癌患者外周静脉血（称为“ p-”）的血清STN水平，我们将其称为“ dp梯度” ”（通过从肿瘤引流静脉血中减去外周静脉血中的血清浓度获得）的144名患者。比较了STN和癌胚抗原（CEA）的预后价值。将患者分为低或高p-抗原组和低，中或高d-p梯度组。单因素和多因素分析显示，高STN d-p梯度，高p-CEA或高CEA d-p梯度都是手术后患者预后不良的独立变量，与阶段不同。总之，高STN d-p梯度可预测结直肠癌切除后预后不良，而p-STN并非独立于分期。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号