Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-Producing Enterobacteriaceae.

Livermore DM; Mushtaq S; Warner M; Zhang J; Maharjan S; Doumith M; Woodford N

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Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-Producing Enterobacteriaceae.

机译：NXL104与头孢他啶和氨曲南的组合对产生碳青霉烯酶的肠杆菌科的活性。

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Combinations of NXL104 with ceftazidime and aztreonam were tested against carbapenem-resistant members of the Enterobacteriaceae. Ceftazidime-NXL104 was active against strains with the OXA-48 enzyme or with combinations of impermeability and an extended-spectrum beta-lactamase (ESBL) or AmpC enzyme and also against most Klebsiella spp. with the KPC enzyme, but metallo-beta-lactamase producers were resistant. Aztreonam-NXL104 was active against all carbapenemase producers at 4 and 4 mug/ml, including those with metallo-beta-lactamases.

机译：测试了NXL104与头孢他啶和氨曲南的组合，以抵抗肠杆菌科细菌对碳青霉烯类的耐药。头孢他啶-NXL104对带有OXA-48酶或不渗透性和超广谱β-内酰胺酶（ESBL）或AmpC酶的菌株具有活性，也对大多数克雷伯菌属具有活性。用KPC酶，但金属β-内酰胺酶生产者有抵抗力。 Aztreonam-NXL104对所有碳青霉烯酶生产商均具有4和4杯/毫升的活性，包括那些具有金属β-内酰胺酶的活性。

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《Antimicrobial agents and chemotherapy.》 |2011年第1期|共5页
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Livermore DM; Mushtaq S; Warner M; Zhang J; Maharjan S; Doumith M; Woodford N;
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正文语种 eng
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1. Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-Producing Enterobacteriaceae. [J] . Livermore DM, Mushtaq S, Warner M, Antimicrobial agents and chemotherapy. . 2011,第1期

机译：NXL104与头孢他啶和氨曲南的组合对产生碳青霉烯酶的肠杆菌科的活性。
2. In Vitro Activities of Ceftazidime-Avibactam, Aztreonam-Avibactam, and a Panel of Older and Contemporary Antimicrobial Agents against Carbapenemase-Producing Gram-Negative Bacilli [J] . Vasoo Shawn, Cunningham Scott A., Cole Nicolynn C., Antimicrobial agents and chemotherapy. . 2015,第12期

机译：头孢他啶-阿维巴坦，Aztreonam-阿维巴坦和一组较老和当代的抗生羧胺酶产生革兰氏阴性杆菌的抗菌剂的体外活性。
3. Activity of chequerboard combinations of ceftaroline and NXL104 versus beta-lactamase-producing Enterobacteriaceae. [J] . Mushtaq S, Warner M, Williams G, The Journal of Antimicrobial Chemotherapy . 2010,第7期

机译：头孢洛林和NXL104的棋盘组合与产生β-内酰胺酶的肠杆菌科细菌的活性。
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6. Activities of NXL104 Combinations with Ceftazidime and Aztreonam against Carbapenemase-Producing Enterobacteriaceae [O] . David M. Livermore, Shazad Mushtaq, Marina Warner, 2011

机译：NXL104与头孢他啶和氨曲南的组合对产碳青霉烯酶肠杆菌科的活性
7. Activities of NXL104 Combinations with Ceftazidime and Aztreonam against Carbapenemase-Producing Enterobacteriaceae [O] . Livermore, DM, Mushtaq, S., Warner, M., 2011

机译：NXL104与头孢他啶和氨曲南组合对产碳青霉烯酶肠杆菌科的活性

Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-Producing Enterobacteriaceae.

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