A novel insertion sequence, ISAba10, inserted into ISAba1 adjacent to the bla(OXA-23) gene and disrupting the outer membrane protein gene carO in Acinetobacter baumannii.

Lee Y; Kim CK; Lee H; Jeong SH; Yong D; Lee K

首页> 外文期刊>Antimicrobial agents and chemotherapy. >A novel insertion sequence, ISAba10, inserted into ISAba1 adjacent to the bla(OXA-23) gene and disrupting the outer membrane protein gene carO in Acinetobacter baumannii.

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A novel insertion sequence, ISAba10, inserted into ISAba1 adjacent to the bla(OXA-23) gene and disrupting the outer membrane protein gene carO in Acinetobacter baumannii.

机译：一种新的插入序列ISAba10，插入到与bla（OXA-23）基因相邻的ISAba1中，并破坏鲍曼不动杆菌中的外膜蛋白基因carO。

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We investigated an outbreak caused by carbapenem-resistant Acinetobacter baumannii carrying the bla(OXA-23) gene. A novel insertion sequence (IS), named ISAba10, was found to be inserted into the ISAba1 element preceding the bla(OXA-23) gene in a group of isolates showing higher carbapenem MICs. The presence of ISAba10 was associated with increased OXA-23 expression, likely by providing additional promoter sequences. ISAba10 was also inserted into the carO outer membrane protein gene in most of these isolates.

机译：我们调查了由携带bla（OXA-23）基因的耐碳青霉烯的鲍曼不动杆菌引起的暴发。发现一个名为ISAba10的新插入序列（IS）被插入到显示较高碳青霉烯MIC的一组分离物中bla（OXA-23）基因之前的ISAba1元件中。 ISAba10的存在与OXA-23表达增加有关，可能是通过提供其他启动子序列来实现的。 ISAba10还插入了大多数这些分离物中的carO外膜蛋白基因中。

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《Antimicrobial agents and chemotherapy.》 |2011年第1期|共3页
作者
Lee Y; Kim CK; Lee H; Jeong SH; Yong D; Lee K;
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正文语种 eng
中图分类治疗学;
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1. A novel insertion sequence, ISAba10, inserted into ISAba1 adjacent to the bla(OXA-23) gene and disrupting the outer membrane protein gene carO in Acinetobacter baumannii. [J] . Lee Y, Kim CK, Lee H, Antimicrobial agents and chemotherapy. . 2011,第1期

机译：一种新的插入序列ISAba10，插入到与bla（OXA-23）基因相邻的ISAba1中，并破坏鲍曼不动杆菌中的外膜蛋白基因carO。
2. Channel formation by CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii. [J] . Siroy A, Molle V, Lemaitre Guillier C, Antimicrobial agents and chemotherapy. . 2005,第12期

机译：CarO（鲍曼不动杆菌的与碳青霉烯耐药相关的外膜蛋白）形成通道。
3. Acinetobacter baumannii transfers the bla(NDM-1) gene via outer membrane vesicles i transfers the bla(NDM-1) gene via outer membrane vesicles [J] . Chatterjee Somdatta, Mondal Ayan, Mitra Shravani, The Journal of Antimicrobial Chemotherapy . 2017,第8期

机译：通过外膜囊泡将BLA（NDM-1）基因转移到外膜囊泡，转移到BAUMANNII，通过外膜囊泡转移BLA（NDM-1）基因
4. The use of insertion sequences to analyse gene function in thiobacilus ferrooxidans: a case study involving cytochrome c-type biogenesis proteins in iron oxidation [C] . D.S.Holmes, E.Jedlicki, M.E.Cabrejos, International biohydrometallurgy symposium;IBS'99 . 1999

机译：利用插入序列分析氧化硫硫杆菌的基因功能：一个涉及铁氧化中细胞色素c型生物合成蛋白的案例研究
5. Characterization of the gene encoding Omp85, a novel outer membrane protein of Neisseria gonorrhoeae and introduction of genes into Neisseria gonorrhoeae. [D] . Reschke, Dennis Karl. 1998

机译：编码淋病奈瑟氏球菌的新型外膜蛋白Omp85的基因的鉴定，并将基因导入淋病奈瑟氏球菌。
6. A Novel Insertion Sequence ISAba10 Inserted into ISAba1 Adjacent to the blaOXA-23 Gene and Disrupting the Outer Membrane Protein Gene carO in Acinetobacter baumannii [O] . Yangsoon Lee, Chang-Ki Kim, Hyukmin Lee, 2011

机译：一个新的插入序列ISAba10插入到与blaOXA-23基因相邻的ISAba1中并破坏鲍曼不动杆菌中的外膜蛋白基因carO
7. A Novel Insertion Sequence, ISAba10, Inserted into ISAba1 Adjacent to the blaOXA-23 Gene and Disrupting the Outer Membrane Protein Gene carO in Acinetobacter baumannii ▿ † [O] . Lee, Yangsoon, Kim, Chang-Ki, Lee, Hyukmin, 2010

机译：一种新的插入序列ISAba10，插入到blaOXA-23基因附近的ISAba1中并破坏鲍曼不动杆菌中的外膜蛋白基因carO▿†
8. Protection Against Scrub Typhus by a Plasmid Vaccine Encoding the 56-KD Outer Membrane Protein Antigen Gene [R] . 2005

机译：用编码56-KD外膜蛋白抗原基因的质粒疫苗防治丛林斑疹伤寒

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A novel insertion sequence, ISAba10, inserted into ISAba1 adjacent to the bla(OXA-23) gene and disrupting the outer membrane protein gene carO in Acinetobacter baumannii.

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