The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes.

Pradel E; Pages JM

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The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes.

机译：AcrAB-TolC外排泵有助于医院病原菌产气肠杆菌中的多药耐药性。

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We identified the genes encoding the AcrA-AcrB-TolC efflux pump in Enterobacter aerogenes and constructed acrAB and tolC mutants from a multidrug-resistant isolate. Both derivatives were more susceptible to antibiotics than the parental strain. Sequence analysis and complementation experiments revealed that the multidrug-resistant isolate is an acrR mutant.

机译：我们鉴定了在产气肠杆菌中编码AcrA-AcrB-TolC外排泵的基因，并从耐多药分离株中构建了acrAB和tolC突变体。与亲本菌株相比，两种衍生物对抗生素更敏感。序列分析和互补实验表明，耐多药分离株是acrR突变体。

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《Antimicrobial agents and chemotherapy.》 |2002年第8期|共4页
作者
Pradel E; Pages JM;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
Enterobacter aerogenes bacterium; Multi-Drug Resistance; encoding; mutant;

机译：产气肠杆菌;多药耐药;编码;突变;

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1. The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes. [J] . Pradel E, Pages JM Antimicrobial agents and chemotherapy. . 2002,第8期

机译：AcrAB-TolC外排泵有助于医院病原菌产气肠杆菌中的多药耐药性。
2. Effect of transcriptional activators SoxS, RobA, and RamA on expression of multidrug efflux pump AcrAB-TolC in Enterobacter cloacae [J] . PérezA., PozaM., ArandaJ., Antimicrobial agents and chemotherapy. . 2012,第12期

机译：转录激活因子SoxS，RobA和RamA对阴沟肠杆菌多药外排泵AcrAB-TolC表达的影响
3. Effect of transcriptional activators SoxS, RobA, and RamA on expression of multidrug efflux pump AcrAB-TolC in Enterobacter cloacae [J] . PérezA., PozaM., ArandaJ., Antimicrobial agents and chemotherapy. . 2012,第12期

机译：转录激活因子SoxS，RobA和RamA对阴沟肠杆菌多药外排泵AcrAB-TolC表达的影响
4. Multidrug Efflux Pumps of Gram-Negative Bacteria [C] . Hiroshi Nikaido Controlled Release Society annual meeting . 2004

机译：革兰氏阴性菌的多药外排泵
5. Probing the Structure of the Small Multidrug Resistance Efflux Pump EmrE by Solid-State Nuclear Magnetic Resonance Spectroscopy. [D] . Banigan, James R. 2015

机译：用固态核磁共振波谱探测小型多药外排泵EmrE的结构。
6. The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes [O] . Elizabeth Pradel, Jean-Marie Pagès 2002

机译：AcrAB-TolC外排泵有助于医院病原菌产气肠杆菌中的多药耐药性
7. The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes [O] . Pradel, Elizabeth, Pagès, Jean-Marie 2002

机译：AcrAB-TolC外排泵有助于医院病原菌产气肠杆菌中的多药耐药性

The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes.

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