In Vitro activity of the new azole isavuconazole (BAL4815) compared with six other antifungal agents against 162 Cryptococcus neoformans isolates from Cuba.

Illnait-Zaragozi MT; Martinez GF; Curfs-Breuker I; Fernandez CM; Boekhout T; Meis JF

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In Vitro activity of the new azole isavuconazole (BAL4815) compared with six other antifungal agents against 162 Cryptococcus neoformans isolates from Cuba.

机译：与其他六种抗真菌药相比，新的唑基伊沙康康唑（BAL4815）的体外活性对来自古巴的162株新隐球菌有所隔离。

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Cuban Cryptococcus isolates (n = 165) were tested in vitro against amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole, giving MIC90 values of 0.25, 8, 4, 0.25, 0.125, 0.016, and 0.016 microg/ml, respectively. Isavuconazole and posaconazole seem to be potentially active drugs for treating cryptococcal infections.

机译：古巴隐球菌分离物（n = 165）在体外针对两性霉素B，氟胞嘧啶，氟康唑，伊曲康唑，伏立康唑，泊沙康唑和伊沙康康唑进行了体外测试，其MIC90值为0.25、8、4、0.25、0.125、0.016和0.016 microg / ml ，分别。伊沙康康唑和泊沙康唑似乎是治疗隐球菌感染的潜在活性药物。

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《Antimicrobial agents and chemotherapy.》 |2008年第4期|共3页
作者
Illnait-Zaragozi MT; Martinez GF; Curfs-Breuker I; Fernandez CM; Boekhout T; Meis JF;
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正文语种 eng
中图分类治疗学;
关键词
In Vitro; posaconazole; Cuba; Cryptococcus neoformans; Azoles; 古巴; 隐球菌; 新型; 氮杂茂类;

机译：In Vitro;posaconazole;Cuba;Cryptococcus neoformans;Azoles;古巴;隐球菌;新型;氮杂茂类;

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1. In Vitro activity of the new azole isavuconazole (BAL4815) compared with six other antifungal agents against 162 Cryptococcus neoformans isolates from Cuba. [J] . Illnait-Zaragozi MT, Martinez GF, Curfs-Breuker I, Antimicrobial agents and chemotherapy. . 2008,第4期

机译：与其他六种抗真菌药相比，新的唑基伊沙康康唑（BAL4815）的体外活性对来自古巴的162株新隐球菌有所隔离。
2. In vitro activity of the synthetic lipopeptide PAL-Lys-Lys-NH(2) alone and in combination with antifungal agents against clinical isolates of Cryptococcus neoformans. [J] . Barchiesi F, Giacometti A, Cirioni O, Peptides: An International Journal . 2007,第8期

机译：合成脂肽PAL-Lys-Lys-NH（2）的体外活性单独和与抗真菌药联合使用对新型隐球菌临床分离株的体外活性。
3. In vitro susceptibility of environmental Cryptococcus neoformans variety neoformans isolates from Turkey to six antifungal agents, including SCH56592 and voriconazole. [J] . Yildiran ST, Saracli MA, Fothergill AW, European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology . 2000,第4期

机译：来自土耳其的新型环境隐球菌变种新形式分离株对六种抗真菌剂（包括SCH56592和伏立康唑）的体外敏感性。
4. Three-Dimensional Model of Lanosterol 14α-Demethylase from Cryptococcus neoformans: Active-Site Characterization and Insights into Azole Binding [C] . Chunquan Sheng, Wannian Zhang, Zhenyuan Miao, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：新型隐球菌羊毛甾醇14α-脱甲基酶的三维模型：主动站点特征和洞见绑定。
5. Investigation of higher plants for potential antiinfective agents: Part I. Isolation and antimicrobial activity of fusaric acid and dehydrofusaric acid from Fusarium oxysporum and Part II. Isolation and structure elucidation of components of Baphia nitida Lodd and Part III. Evaluation of higher plant constituents in a novel assay for the potential inhibition of phenoloxidase in Cryptococcus neoformans. [D] . Hatch, Deanna Mari. 1995

机译：高等植物潜在抗感染药的研究：第一部分。尖孢镰刀菌中富马酸和脱氢富马酸的分离和抑菌活性，第二部分。楠（Baphia nitida Lodd）和第三部分的成分的分离和结构解析。在新型测定中评估新型隐球菌中酚氧化酶的潜在抑制作用。
6. In Vitro Activity of the New Azole Isavuconazole (BAL4815) Compared with Six Other Antifungal Agents against 162 Cryptococcus neoformans Isolates from Cuba [O] . Maria-Teresa Illnait-Zaragozi, Gerardo F. Martínez, Ilse Curfs-Breuker, 2008

机译：新的Azole Isavuconazole（BAL4815）与其他六种抗真菌药对162种来自古巴的新型隐球菌的体外活性
7. In Vitro activity of the new azole isavuconazole (BAL4815) compared with six other antifungal agents against 162 Cryptococcus neoformans isolates from Cuba. [O] . Illnait-Zaragozi, M.T., Martinez, G.F., Curfs-Breuker, I., 2008

机译：与其他六种抗真菌药相比，新的唑基伊沙康康唑（BAL4815）的体外活性对来自古巴的162株新隐球菌分离。

In Vitro activity of the new azole isavuconazole (BAL4815) compared with six other antifungal agents against 162 Cryptococcus neoformans isolates from Cuba.

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