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Early ovarian lancer: Prevention, diagnosis, treatment

机译:卵巢早期采血者:预防,诊断,治疗

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摘要

PURPOSE: To review medical evidence related to screening for ovarian cancer, diagnosis, and treatment EPIDEMIOLOGY: More than 22 000 women are diagnosed with ovarian cancer annually. As many as 16 210 will die from the malignancy, primarily as a result of the advanced stage of disease at diagnosis. Most women with ovarian cancer do not have any strong risk factors for the disease. REVIEW SUMMARY: Medical evidence does not support the use of current screening modalities for ovarian cancer. However, astute clinical observation may help with an early diagnosis. This article reviews frequent signs and symptoms that may alert primary care clinicians to a possible diagnosis of ovarian cancer. Although these symptoms are characteristic of a number of conditions, certain symptom clusters have been associated specifically with ovarian cancer. TYPE OF AVAILABLE EVIDENCE: Nationally recognized consensus guidelines; patient surveys; randomized controlled trials; genetic data; pathologic findings. GRADE OF AVAILABLE EVIDENCE: Poor to good. CONCLUSION: Severe, frequent symptoms of recent onset warrant further diagnostic investigation. Primary care clinicians can play a key role in promoting earlier diagnosis and treatment, which substantially improves overall survival rates.
机译:目的:审查与卵巢癌筛查,诊断和治疗有关的医学证据流行病学:每年有超过22 000名妇女被诊断出患有卵巢癌。多达16210人死于恶性肿瘤,这主要是由于诊断时疾病晚期所致。大多数患有卵巢癌的女性对该病没有任何强烈的危险因素。综述:医学证据不支持使用当前的卵巢癌筛查方法。但是,精明的临床观察可能有助于早期诊断。本文介绍了可能会提醒初级保健临床医生卵巢癌诊断的常见症状和体征。尽管这些症状是许多疾病的特征,但某些症状群已与卵巢癌特别相关。可用的证据类型:全国公认的共识准则;病人调查;随机对照试验;遗传数据;病理结果。可用的证据等级:差强人意。结论:近期发作的严重,频繁症状值得进一步的诊断研究。初级保健临床医生可以在促进早期诊断和治疗中发挥关键作用,从而大大提高整体生存率。

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