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首页> 外文期刊>Aquatic Living Resources >A short-review of brown ring disease, a vibriosis affecting clams,Ruditapes philippinarum and Ruditapes decussates
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A short-review of brown ring disease, a vibriosis affecting clams,Ruditapes philippinarum and Ruditapes decussates

机译：棕环病的简短回顾，这是一种影响蛤s，菲律宾蛤仔和小蛤仔的弧菌病

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摘要

Brown ring disease (BRD) in Ruditapes philippinarum and Ruditapes decussatus is a shell disease caused by Vibrio tapetis. This disease has begun in 1987 in clams beds in Brittany (France) and then has spread along the European Atlantic coast. Since about fifteen years, research on BRD has progress a lot and the purpose of this review is to give a short description of BRD in clams in retrospect and in addition of recent and pertinent results. Diagnosis including isolation, biochemical, serological and molecular characterization has been developed to identify and detect the pathogen. Therefore, Vibrio tapetis like strains has been detected in other host specie, in cultured fishes during mortalities, such as the wrasse, Symphodus melops in Norway and the halibut, Hippoglossus hippoglossus in Scotland. Mechanisms of host-pathogen interactions modulated by environmental factors were studied using in vivo bacterial challenge and in vitro bio-assays. According to these studies, adherence and cytotoxic factors have been yet identified as virulence factors; identification and characterization of virulence genes are in progress. Field and experimental studies confirmed the significant e.ect of temperature on the development of BRD and on clam defense related activities. A significant increase in temperature over 21 degree C may have a preventive effect on the development of the disease.
机译：菲律宾蛤仔和南美蛤仔中的棕环病（BRD）是一种由胶带菌弧菌引起的壳病。这种疾病始于1987年在法国布列塔尼的蛤beds床上，然后在欧洲大西洋沿岸传播。自大约15年以来，对BRD的研究取得了很大进展，本综述的目的是回顾一下蛤中BRD的简短情况，并提供近期和相关的结果。已经开发出包括分离，生化，血清学和分子表征在内的诊断以鉴定和检测病原体。因此，在其他寄主物种中，在死亡期间的养殖鱼类中也检测到了类似弧菌的菌株，例如濑鱼，挪威的Symphodus幼鱼和大比目鱼，苏格兰的河马。使用体内细菌攻击和体外生物测定研究了环境因素调节的宿主-病原体相互作用的机制。根据这些研究，依从性和细胞毒性因子已被确定为致病因子。毒力基因的鉴定和表征正在进行中。现场和实验研究证实了温度对BRD发育和与蛤lam防御有关的活动的重要影响。温度超过21摄氏度时明显升高可能会对疾病的发展产生预防作用。

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