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Historical aspects of botulinum toxin used clinically: Part I: is that the right serotype?

机译:历史方面的使用肉毒杆菌毒素临床:第一部分:正确的血清型吗?

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摘要

The basis of botulinum toxin use as a neuromedicine started over 40 years ago when the first serotype was chosen for key initial studies in monkeys by Alan Scott and colleagues in the USA. From that point on, the protein has been used extensively andworldwide for treatment of many clinical conditions. But much remains to be documented about the earliest times, the very beginning years when critical choices and decisions were made. This first article in a series looks at the choice of the first botulinum toxin serotype used and why that choice was made.
机译:肉毒杆菌毒素作为的基础神经医学开始超过40年前的时候第一个血清型是选择关键的初步研究在猴子的艾伦·斯科特和他的同事们美国。广泛使用andworldwide治疗许多临床条件。记录最早的倍,年开始选择和关键决策。系列看着肉毒第一的选择毒素血清型和为什么选择使用。

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