...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Aquaculture >Antibiograms and the estimation of epidemiological cut off values for Vibrio ichthyoenteri isolated from larval olive flounder, Paralichthys olivaceus.
【24h】

Antibiograms and the estimation of epidemiological cut off values for Vibrio ichthyoenteri isolated from larval olive flounder, Paralichthys olivaceus.

机译：分离自幼体比目鱼 Paralichthys olivaceus 的 ichchyoenteri 的抗菌素谱和流行病学临界值的估计。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this study, thirty-five strains of Vibrio ichthyoenteri, which is a causative agent of bacterial enteritis, were isolated from diseased larval olive flounder (Paralichthys olivaceus) (n=35) taken from a hatchery located in Jeju Island. The minimum inhibitory concentration (MIC) of nine antimicrobials was determined for each strain using the Etest or the CLSI broth microdilution method. The MIC distributions were used to generate epidemiological cut off values using normalized resistance interpretation (NRI). The wild type cut off values (COwt) for OTC, ERY, FLU, NA, OXA and CFX were <=2.0, 16.0, 1.5, 3.0, 0.5 and 0.5 mg/L, respectively. Using these COwt values, only isolates from 2007 were treated as non wild-type (NWT) for FLU, NA, OXA and CFX. Most isolates retrieved in 2009 were categorized as wild type (WT) for tetracycline and erythromycin. However, NRI analysis could not be applied to three of the antimicrobials (ampicillin, amoxicillin and trimethoprim/sulfamethoxazole); thus, visual examinations were conducted to determine COwt. We used a limit of 2 mg/L for both ampicillin and amoxicillin, and most strains were classified as NWT for the antibiotics, indicating that beta-lactam antibiotics are not very efficient for the treatment of this disease. Based on the MIC values, V. ichthyoenteri seemed to be sensitive to trimethoprim/sulfamethoxazole. The results of this study showed that the NRI-derived COwt values for the six agents (tetracycline, erythromycin, FLU, NA, OXA and CFX) can be used as provisional epidemiological cut off values.
机译：在这项研究中，从患病幼虫比目鱼（ Paralichthys olivaceus ）（）中分离了35株细菌性肠炎的致病菌 Vichio ichthyoenteri 。 n = 35）是从济州岛的一处孵化场获取的。使用Etest或CLSI肉汤微稀释法确定了每种菌株的9种抗菌剂的最低抑菌浓度（MIC）。 MIC分布用于使用归一化抗性解释（NRI）生成流行病学临界值。 OTC，ERY，FLU，NA，OXA和CFX的野生型截止值（CO wt ）分别<= 2.0、16.0、1.5、3.0、0.5和0.5 mg / L。使用这些CO wt 值，仅将2007年的分离物的FLU，NA，OXA和CFX视为非野生型（NWT）。 2009年检索到的大多数分离株都属于四环素和红霉素的野生型（WT）。但是，NRI分析不能应用于三种抗菌药物（氨苄青霉素，阿莫西林和甲氧苄氨嘧啶/磺胺甲基异恶唑）。因此，进行目测以确定CO wt 。我们对氨苄青霉素和阿莫西林均使用2 mg / L的限量，大多数菌株被归类为NWT抗生素，这表明β-内酰胺类抗生素对这种疾病的治疗不是很有效。基于MIC值， V。 ichthyoenteri 似乎对甲氧苄啶/磺胺甲恶唑敏感。这项研究的结果表明，六种药物（四环素，红霉素，FLU，NA，OXA和CFX）的NRI衍生的CO wt 值可以用作临时流行病学临界值。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号