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首页> 外文期刊>Archives of disease in childhood >Blood pressure in sleep disordered breathing.
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Blood pressure in sleep disordered breathing.

机译:睡眠中的血压呼吸紊乱。

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摘要

AIMS: To investigate blood pressure (BP) in children with sleep disordered breathing (SDB). METHODS: BP was measured during single night polysomnography in 23 suspected SDB child patients with adenotonsillar hypertrophy, but without respiratory or heart failure, or coma. The age related changes of the observed BP were normalised to the BP index. The BP indices were examined in relation to SDB measures, such as the desaturation time (percentage of time with oxygen saturation (SaO2) <90% against the total sleep time), SaO2 nadir, apnoea-hypopnoea index (AHI), and arousal index, in addition to age and body mass index (BMI). RESULTS: The systolic BP index during rapid eye movement sleep (REMS) tended to correlate with AHI, while the diastolic index during REM sleep showed a significant correlation with AHI. The BP indices during non-REMS and wakefulness showed no correlation with the parameters obtained. Patients with an AHI of 10 or more (n = 7, AHIhigh) had significantly higher systolic and diastolic BP indices during both wakefulness and REMS, compared with those with an AHI of less than 10 (n = 16, AHIlow). Two patients in AHIhigh showed no sleep related dip of diastolic BP, and three patients in AHIlow lacked the sleep related dip in systolic BP. By means of multiple regression analysis, age, BMI, and AHI were found to be significant predictor variables of the systolic BP index during REMS. CONCLUSIONS: BP in paediatric SDB patients is positively correlated with the degree of SDB.
机译:目的:研究睡眠呼吸障碍(SDB)儿童的血压(BP)。方法:在23例怀疑为SDB的腺扁桃体肥大但没有呼吸或心力衰竭或昏迷的儿童中,单夜多导睡眠图测量血压。将观察到的BP的与年龄相关的变化标准化为BP指数。检查了与SDB量度有关的BP指数,例如去饱和时间(氧饱和度(SaO2)的时间百分比<90%相对于总睡眠时间),SaO2最低点,呼吸暂停-低通气指数(AHI)和唤醒指数,以及年龄和体重指数(BMI)。结果:快速眼动睡眠(REMS)期间的收缩压指数倾向于与AHI相关,而REM睡眠期间的舒张指数与AHI显着相关。非REMS和清醒期间的BP指数与所获得的参数无关。与AHI低于10的患者(n = 16,AHIlow)相比,AHI为10或更高(n = 7,AHIhigh)的患者在清醒和REMS期间的收缩压和舒张压BP指数均显着更高。 AHIhigh的2例患者没有显示与舒张压相关的睡眠下降,AHIlow的3例患者的收缩压没有与睡眠相关的下降。通过多元回归分析,发现年龄,BMI和AHI是REMS期间收缩压BP指数的重要预测变量。结论:小儿SDB患者的血压与SDB的程度呈正相关。

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