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Prospective study of non-nutritive sucking and feeding skills in premature infants

机译:早产儿非营养性吮吸和喂养技巧的前瞻性研究

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Objective: The aim of the present work was to assess the value of non-nutritive sucking (NNS) measures as predictors of oral feeding performance in comparison to other putative predictors of feeding skills: respiratory support, post-menstrual age (PMA) at birth and the neonatal oral motor assessment score (NOMAS). Methods: This was a prospective, observational study. Cox proportional hazards and non-parametric rank sum tests were used to assess the relationship between NNS and feeding outcome measures. The setting was neonatal intensive care units (NICU) in rural/academic, urban/tertiary centres in the USA. In all, 51 premature infants born between 25 and 34 weeks' PMA, birth weight 1512.3±499.4 g, were included in this study. Interventions were measurement of NNS, standardised feeding advance schedule, performance of NOMAS, and standardised, permissive, oral feeding advance schedule. Main outcome measures were transition time from first to full oral feeding (FOF) and gestational age at FOF. Results: Higher NNS organisation scores predicted shorter transition to FOF (p<0.05): infants with a more organised suck pattern reached independent oral feeding 3 days earlier (16 vs 13 day transition) than infants with more chaotic patterns of suck bursts. Consistency of the suck waves also corresponded with feeding milestones: infants with more regular suck wave pressure deflections became competent oral feeders approximately 3 days earlier than those with irregular suck pressure waves. PMA at birth was inversely associated with PMA at FOF. NOMAS measures were not associated with outcome measures. Conclusions: Measures of NNS organisation and suck consistency constitute useful candidate predictors of feeding performance by premature infants. The results accord with previous findings linking PMA at birth with age at independent feeding.
机译:目的:本研究的目的是评估与其他推定的喂养技能预测指标(呼吸支持,出生时的月经后年龄(PMA))相比,非营养性吮吸(NNS)措施作为口服喂养表现预测指标的价值以及新生儿口腔运动评估评分(NOMAS)。方法:这是一项前瞻性观察研究。考克斯比例风险和非参数秩和检验用于评估NNS与喂养结果测度之间的关系。背景是美国农村/学术,城市/三级中心的新生儿重症监护病房(NICU)。本研究共纳入了51名PMA在25至34周之间出生的早产儿,出生体重1512.3±499.4 g。干预措施包括NNS的测量,标准化的喂食提前时间表,NOMAS的性能以及标准化的,允许的口服喂食提前时间表。主要结局指标是首次进食到完全口服喂养(FOF)的过渡时间以及FOF的胎龄。结果:较高的NNS组织得分预示着向FOF的过渡更短(p <0.05):吸吮方式更有条理的婴儿比吮吸爆发方式更混乱的婴儿提前3天(分别是16天和13天的过渡)进行了独立口服喂养。吮吸波的一致性还与喂养的里程碑相对应:吮吸波压力挠度更规则的婴儿比吮吸波不规则的婴儿早约3天成为合格的口服喂食器。出生时的PMA与FOF时的PMA成反比。 NOMAS指标与结果指标无关。结论:NNS组织和吮吸一致性的量度可以作为预测早产儿喂养性能的有效候选指标。该结果与先前的发现相符,后者将出生时的PMA与独立喂养时的年龄联系起来。

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