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Experimental and theoretical laser-Doppler frequency spectra of a tissuelike model of a human head with capillaries

机译:具有毛细血管的人头组织样模型的实验和理论激光多普勒频谱

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摘要

Laser-Doppler flow measurements with penetration depths from 10 to 30 mm have been performed on a layered model of the human head consisting of a regular array of capillaries with diameters of 340 μm embedded in an epoxy matrix with tissuelike scattering and absorption properties. Monte Carlo simulations and an analytical approach based on diffusing wave spectroscopy have corroborated the measurements and have led to a quantitative description of flow in deep-lying tissue layers with regard to layers near the surface also. The results indicate that it may be possible to measure changes in cortical blood flow even in the presence of a well-perfused scalp.
机译:已在人头的分层模型上执行了穿透深度为10至30 mm的激光多普勒血流测量,该模型由规则排列的直径为340μm的毛细血管嵌在环氧基质中,具有类似组织的散射和吸收特性。蒙特卡罗模拟和基于扩散波谱的分析方法证实了测量结果,并导致对深层组织层中与表面附近层有关的流动进行了定量描述。结果表明,即使在头皮灌注良好的情况下,也有可能测量皮质血流的变化。

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