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In vivo measurements of the wavelength dependence of tissue-scattering coefficients between 760 and 900 nm measured with time-resolved spectroscopy

机译:用时间分辨光谱法在760和900 nm之间对组织散射系数的波长依赖性进行体内测量

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摘要

We present in vivo values for the optical transport coefficients (mu(a), mu(s)') of the adult human forearm, calf, and head from 760 to 900 nm measured with time-resolved spectroscopy. The accuracy of the method is tested with tissue-simulating phantoms. We obtain mu(s)'(lambda) approximate to 1.1 - (5.1 x 10(-4) lambda) mm(-1) (forearm), 1.6 - (8.9 x 10(-4) lambda) mm(-1) (calf), and 1.45 - (6.5 x 10(-4) lambda) mm(-1) (head), where lambda is measured in nanometers. At 800 nm we obtain mu(a) = 0.023 +/- 0.004 mm(-1) (forearm), 0.017 +/- 0.005 mm(-1) (calf), and 0.016 +/- 0.001 mm(-1) (head). Our values differ substantially from published in vitro data. In particular, our transport coefficients for the adult head are substantially lower than previously reported values for adult human cerebral matter and pig skull cortical bone measured in vitro. (C) 1997 Optical Society of America
机译:我们介绍了体内时间值分辨光谱法测量的成年人类前臂,小腿和头部从760至900 nm的光学转运系数(mu(a),mu(s)')。使用组织模拟体模测试该方法的准确性。我们获得的mu(s)'(λ)大约为1.1-(5.1 x 10(-4)lambda)mm(-1)(前臂),1.6-(8.9 x 10(-4)lambda)mm(-1) (小牛)和1.45-(6.5 x 10(-4)λ)mm(-1)(头),其中以纳米为单位测量λ。在800 nm处,我们获得的mu(a)= 0.023 +/- 0.004 mm(-1)(前臂),0.017 +/- 0.005 mm(-1)(小腿)和0.016 +/- 0.001 mm(-1)(头)。我们的值与公开的体外数据有很大不同。特别是,我们成年头的转运系数大大低于先前报道的成年人脑物质和猪头骨皮质骨体外测量值。 (C)1997年美国眼镜学会

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