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首页> 外文期刊>Annals of surgical oncology >Prognosis of perihilar cholangiocarcinoma: hilar bile duct cancer versus intrahepatic cholangiocarcinoma involving the hepatic hilus.
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Prognosis of perihilar cholangiocarcinoma: hilar bile duct cancer versus intrahepatic cholangiocarcinoma involving the hepatic hilus.

机译：肝门周围胆管癌的预后：肝门胆管癌与肝内胆管癌的累及肝门。

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BACKGROUND: Clinically hepatobiliary resection is indicated for both hilar bile duct cancer (BDC) and intrahepatic cholangiocarcinoma involving the hepatic hilus (CCC). The aim of this study was to compare the long-term outcome of BDC and CCC. METHODS: Between 1990 and 2004, we surgically treated 158 consecutive patients with perihilar cholangiocarcinoma. The clinicopathological data on all of the patients were analyzed retrospectively. RESULTS: The overall 3-year survival rate, 5-year survival rate, and median survival time for BDC patients were 48.4%, 38.4 %, and 33.7 months, respectively, and 35.8%, 24.5 %, and 22.7 months, respectively, in CCC patients (P = .033). On multivariate analysis, three independent factors were related to longer survival in BDC patients: achieved in curative resection with cancer free margin (R0) (P = .024, odds ratio 1.862), well differentiated or papillary adenocarcinoma (P = .011, odds ratio 2.135), and absence of lymph node metastasis (P < .001, odds ratio 3.314). Fivefactors were related to longer survival in CCC patients: absence of intrahepatic daughter nodules (P < .001, odds ratio 2.318), CEA level
机译：背景：临床上肝胆切除术适用于肝门部胆管癌（BDC）和肝内胆管癌（CCC）。这项研究的目的是比较BDC和CCC的长期结果。方法：在1990年至2004年之间，我们通过外科手术治疗了158例连续的肝门周围胆管癌患者。回顾性分析所有患者的临床病理资料。结果：BDC患者的总3年生存率，5年生存率和中位生存时间分别为48.4％，38.4％和33.7个月，分别为35.8％，24.5％和22.7个月。 CCC患者（P = .033）。在多变量分析中，三个独立因素与BDC患者的更长生存时间相关：在无癌切缘（R0）的根治性切除术中获得的优势（P = .024，优势比1.862），分化良好或乳头状腺癌（P = .011，优势比率为2.135），并且没有淋巴结转移（P <.001，优势比3.314）。五因素与CCC患者的更长生存时间有关：肝内子结节缺失（P <.001，比值比2.318），CEA水平

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