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首页> 外文期刊>Bone marrow transplantation >Successful treatment of refractory autoimmune haemolytic anaemia in a post-unrelated bone marrow transplant paediatric patient with rituximab.
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Successful treatment of refractory autoimmune haemolytic anaemia in a post-unrelated bone marrow transplant paediatric patient with rituximab.

机译:成功治疗利妥昔单抗无关的骨髓移植儿童患者后的难治性自身免疫性溶血性贫血。

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摘要

Here, we report a case of paediatric beta-thalassaemia major patient who underwent unrelated T cell-non- depleted bone marrow transplantation and developed a complication of autoimmune haemolytic anaemia (AIHA) refractory to corticosteroid and intravenous immunoglobulin therapy. After this child received two doses (375 mg/m(2)/dose) of rituximab (anti-CD20 monoclonal antibody), his AIHA was resolved.
机译:在这里,我们报道了一名小儿β地中海贫血的主要患者,该患者接受了不相关的T细胞未耗竭的骨髓移植,并发展了对糖皮质激素和静脉内免疫球蛋白治疗难治的自身免疫性溶血性贫血(AIHA)并发症。在这个孩子接受了两剂(375 mg / m(2)/剂量)的利妥昔单抗(抗CD20单克隆抗体)后,他的AIHA得到了解决。

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