Pulsatilla saponin D: the antitumor principle from Pulsatilla koreana.

Kim Y; Bang SC; Lee JH; Ahn BZ

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Pulsatilla saponin D: the antitumor principle from Pulsatilla koreana.

机译：白头翁皂苷D：来自白头翁的抗肿瘤原理。

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By bioassay-guided separation, an already known saponin, Pulsatilla saponin D was isolated from the root of Pulsatilla koreana Nakai as a antitumor component when evaluated by in vivo antitumor activity as well as in vitro cytotoxic activity test. It showed potent inhibition rate of tumor growth (IR, 82%) at the dose of 6.4 mg/kg on the BDF1 mice bearing LLC cells.

机译：通过生物测定指导的分离，当通过体内抗肿瘤活性和体外细胞毒性活性测试进行评估时，从朝鲜白头翁的根中分离出一种已知的皂苷，白头翁皂苷D作为抗肿瘤成分。它在荷有LLC细胞的BDF1小鼠上以6.4 mg / kg的剂量显示出有效的肿瘤生长抑制率（IR，82％）。

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《Archives of pharmacal research》 |2004年第9期|共4页
作者
Kim Y; Bang SC; Lee JH; Ahn BZ;
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正文语种 eng
中图分类护理学;
关键词
in vivo; tumor growth; Plant Roots; Marital separation; 植物根;

机译：in vivo;tumor growth;Plant Roots;Marital separation;植物根;

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1. 白头翁水提液中白头翁皂苷B4含量检测方法的建立 [J] . 王建舫农业科学与技术（英文版） . 2015,第008期
2. Pulsatilla saponin D: the antitumor principle from Pulsatilla koreana. [J] . Kim Y, Bang SC, Lee JH, Archives of pharmacal research . 2004,第9期

机译：白头翁皂苷D：来自白头翁的抗肿瘤原理。
3. SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities. [J] . Sang-Won Hong, Kyung Hee Jung, Hee-Seung Lee, Carcinogenesis . 2013,第9期

机译：白头翁皂苷D SB365靶向c-Met并发挥抗血管生成和抗肿瘤活性。
4. SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities. [J] . Sang-Won Hong, Kyung Hee Jung, Hee-Seung Lee, Carcinogenesis . 2013,第9期

机译：SB365，Pulsatilla Saponin D，靶向C-Met并施加抗炎和抗肿瘤活动。
5. Investigation of the Preparation Process for Pulsatilla Chinensis (Bunge) Regel Total Saponins-Hydroxypropyl-β-Cyclodextrin Inclusion Compound Pellets 1 [C] . Zhenhua Chen, Suzhen Liu, Yongmei Guan, International Conference on Materials, Environmental and Biological Engineering . 2015

机译：对脉络膜（Bunge）升值的制备方法进行调查（Bunge）Recel总皂苷 - 羟丙基-β-环糊精包合物颗粒1
6. Phytochemical studies on medicinal plants: Euphorbia ebracteolata, Pulsatilla chinensis, and Gymnema sylvestre. [D] . Ye, Wen-Cai. 2001

机译：药用植物的植物化学研究：大戟（Euphorbia ebracteolata），白头翁（Pulsatilla chinensis）和樟子松（Gymnema sylvestre）。
7. An active molecule from Pulsatilla chinensis Pulsatilla saponin A induces apoptosis and inhibits tumor growth of human colon cancer cells without or with 5-FU [O] . Liming Xu, Guilian Cheng, Yi Lu, -1

机译：来自白头翁的活性分子白头翁皂苷A可以诱导人结肠癌细胞的凋亡并抑制5-FU或不联合5-FU
8. SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities [O] . Sang-Won Hong, Kyung Hee Jung, Hee-Seung Lee, 2013

机译：SB365，Pulsatilla Saponin D，靶向C-Met并施加抗宇生成和抗肿瘤活动

Pulsatilla saponin D: the antitumor principle from Pulsatilla koreana.

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