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Computational fluid dynamics-based hydraulic and hemolytic analyses of a novel left ventricular assist blood pump.

机译:基于计算流体动力学的新型左心室辅助血泵的液压和溶血分析。

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摘要

The advent of various technologies has allowed mechanical blood pumps to become more reliable and versatile in recent decades. In our study group, a novel structure of axial flow blood pump was developed for assisting the left ventricle. The design point of the left ventricular assist blood pump 25 (LAP-25) was chosen at 4 Lpm with 100 mm Hg according to our clinical practice. Computational fluid dynamics was used to design and analyze the performance of the LAP-25. In order to obtain a required hydraulic performance and a satisfactory hemolytic property in the LAP-25 of a smaller size, a novel structure was developed including an integrated shroud impeller, a streamlined impeller hub, and main impeller blades with splitter blades; furthermore, tandem cascades were introduced in designing the diffuser. The results of numerical simulation show the LAP-25 can generate flow rates of 3-5 Lpm at rotational speeds of 8500-10,500 rpm, producing pressure rises of 27.5-148.3 mm Hg with hydraulic efficiency points ranging from 13.4 to 27.5%. Moreover, the fluid field and the hemolytic property of the LAP-25 were estimated, and the mean hemolysis index of the pump was 0.0895% with Heuser's estimated model. In conclusion, the design of the LAP-25 shows an acceptable result.
机译:近几十年来,各种技术的出现使机械血泵变得更加可靠和通用。在我们的研究小组中,开发了一种新型的轴流血泵结构,用于辅助左心室。根据我们的临床实践,左心室辅助血泵25(LAP-25)的设计点选择为4 Lpm和100 mm Hg。计算流体动力学用于设计和分析LAP-25的性能。为了在较小尺寸的LAP-25中获得所需的水力性能和令人满意的溶血特性,开发了一种新颖的结构,包括集成的罩式叶轮,流线型的叶轮毂以及带分流叶片的主叶轮叶片。此外,在设计扩散器时引入了串联级联。数值模拟结果表明,LAP-25在8500-10,500 rpm的转速下可产生3-5 Lpm的流量,产生27.5-148.3 mm Hg的压力升高,液压效率点在13.4至27.5%之间。此外,估计了LAP-25的流场和溶血特性,在Heuser估计模型中,泵的平均溶血指数为0.0895%。总之,LAP-25的设计显示出可接受的结果。

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