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首页> 外文期刊>Artificial Organs >The importance of dQ/dt on the flow field in a turbodynamic pump with pulsatile flow.
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The importance of dQ/dt on the flow field in a turbodynamic pump with pulsatile flow.

机译：dQ / dt对具有脉动流的涡轮动力泵的流场的重要性。

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Fluid dynamic analysis of turbodynamic blood pumps (TBPs) is often conducted under steady flow conditions. However, the preponderance of clinical applications for ventricular assistance involves unsteady, pulsatile flow-due to the residual contractility of the native heart. This study was undertaken to demonstrate the importance of pulsatility and the associated time derivative of the flow rate (dQ/dt) on hemodynamics within a clinical-scale TBP. This was accomplished by performing flow visualization studies on a transparent model of a centrifugal TBP interposed within a cardiovascular simulator with controllable heart rate and stroke volume. Particle image velocimetry triggered to both the rotation angle of the impeller and phase of the cardiac cycle was used to quantify the velocity field in the outlet volute and in between the impeller blades for 16 phases of the cardiac cycle. Comparison of the unsteady flow fields to corresponding steady conditions at the same (instantaneous) flow rates revealed marked differences. In particular, deceleration of flow was found to promote separation within the outlet diffuser, while acceleration served to stabilize the velocity field. The notable differences between the acceleration and deceleration phases illustrated the prominence of inertial fluid forces. These studies emphasize the importance of dQ/dt as an independent variable for thorough preclinical validation of TBPs intended for use as a ventricular assist device.
机译：涡轮动力血泵（TBP）的流体动力分析通常是在稳定流量条件下进行的。然而，由于天然心脏的残余收缩性，临床上用于心室辅助的优势包括不稳定的搏动性血流。进行这项研究是为了证明搏动性的重要性以及流速（dQ / dt）的相关时间导数在临床规模的TBP内对血流动力学的影响。这是通过在透明的TBP模型上进行流量可视化研究来实现的，该透明模型插入在具有可控心率和中风量的心血管模拟器中。触发叶轮旋转角度和心动周期相位的粒子图像测速用于量化心动周期16个相位的出口蜗壳内和叶轮叶片之间的速度场。在相同（瞬时）流量下，非稳态流场与相应的稳态条件的比较显示出显着差异。特别地，发现流量的减速促进了出口扩散器内的分离，而加速度则起到了稳定速度场的作用。加速和减速阶段之间的显着差异说明了惯性流体力的突出。这些研究强调了dQ / dt作为独立变量对于彻底临床前验证用作心室辅助设备的TBP的重要性。

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