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首页> 外文期刊>Asia-Pacific journal of public health >Serological Prevalence of Leptospirosis Among Rural Communities in the Rejang Basin, Sarawak, Malaysia
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Serological Prevalence of Leptospirosis Among Rural Communities in the Rejang Basin, Sarawak, Malaysia

机译:马来西亚砂拉越里让盆地农村社区中钩端螺旋体病的血清学流行率

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摘要

Leptospirosis is an important zoonotic disease globally and is endemic in Malaysia. A study was conducted in the Rejang basin of Sarawak from June 2011 to May 2013 to determine the seroprevalence of leptospirosis among the communities and dominant infecting Leptospira serovars. A total of 508 human sera were analyzed using ELISA and the microscopic agglutination test (MAT). The seroprevalence of leptospirosis in the study area was 37.4%, with the highest prevalence in Kapit division. More women were positive for leptospirosis (59.5%), and the mean age of seropositive individuals was 42.2 (SD = 18.7) years. Antibody titers between 1: 50 and 1: 1600 were reported, and serovars djasiman (22.1%), shermani (13.2%), and pomona (7.9%) predominated, with varied distribution between geographical locations. This study highlighted the endemicity and diversity of existing Leptospira serovars within the community. This information should be communicated to local health personnel and communities at risk, and rapid diagnostic capability should be made available to local health facilities.
机译:钩端螺旋体病是全球重要的人畜共患病,在马来西亚很流行。 2011年6月至2013年5月在砂拉越的Rejang盆地进行了一项研究,以确定社区和主要感染性钩端螺旋体血清型中钩端螺旋体的血清阳性率。使用ELISA和显微凝集试验(MAT)对总共508个人的血清进行了分析。研究区钩端螺旋体病的血清流行率为37.4%,在Kapit分区中患病率最高。钩端螺旋体病阳性的女性更多(59.5%),血清阳性患者的平均年龄为42.2岁(SD = 18.7)。据报道,抗体效价在1:50和1:1600之间,且血清型djasiman(22.1%),shermani(13.2%)和pomona(7.9%)占主导地位,并且地理位置之间的分布不同。这项研究强调了社区中现有钩端螺旋体血清型的特有性和多样性。应将此信息传达给有风险的当地卫生人员和社区,并应向当地卫生机构提供快速诊断能力。

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