Severe pancytopenia due to acute folate deficiency despite normal folate erythrocyte level

Huguenin Antoine; Barraud Sara; Daliphard Sylvie; Marot Didier; Garnotel Roselyne; Bani-Sadr Firouze

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Severe pancytopenia due to acute folate deficiency despite normal folate erythrocyte level

机译：尽管叶酸红细胞水平正常，但由于急性叶酸缺乏导致严重的全血细胞减少

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We report the case of an alcoholic patient with severe pancytopenia with lowplasma folate level but normal erythrocyte folates and cobalamin levels. The bone marrow smear concluded to a pancytopenia due to folates and/or cobalamin deficiency. Severe pancytopenia due to acute plasma folate deficiency can be observed despite normal erythrocyte folates level which reflects the organism's folates store.

机译：我们报告一例重度全血细胞减少症，低血浆叶酸水平但正常的红细胞叶酸和钴胺素水平的酒精中毒患者。由于叶酸和/或钴胺素缺乏症，骨髓涂片可导致全血细胞减少。尽管正常的红血球叶酸水平反映了生物体的叶酸储存，但仍可观察到由于急性血浆叶酸缺乏导致的严重全血细胞减少。

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来源
《Annales de biologie clinique》 |2016年第3期|共4页
作者
Huguenin Antoine; Barraud Sara; Daliphard Sylvie; Marot Didier; Garnotel Roselyne; Bani-Sadr Firouze;
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正文语种 fre
中图分类生物化学检验、临床检验;
关键词
pancytopenia; acute folate deficiency; megaloblastic anemia; alcohol-associated pancytopenia; alcohol-blood disorders;

机译：全血细胞减少症;急性叶酸缺乏症;巨幼细胞性贫血;酒精相关的全血细胞减少症;酒精-血液异常;

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1. Severe pancytopenia due to acute folate deficiency despite normal folate erythrocyte level [J] . Huguenin Antoine, Barraud Sara, Daliphard Sylvie, Annales de biologie clinique . 2016,第3期

机译：尽管叶酸红细胞水平正常，但由于急性叶酸缺乏导致严重的全血细胞减少
2. Olanzapine and pancytopenia with severe folate deficiency. [J] . Maurier F, Petitpain N, Guichard JF, European journal of clinical pharmacology . 2010,第5期

机译：奥氮平和全血细胞减少症伴严重叶酸缺乏。
3. Olanzapine and pancytopenia with severe folate deficiency [J] . F. Maurier, N. Petitpain, J.-F. Guichard, European Journal of Clinical Pharmacology . 2010,第5期

机译：奥氮平和全血细胞减少症伴严重叶酸缺乏
4. A Petri Net model to simulate and analyse cerebral folate deficiency and hyperhomocysteinemia effects in Autism Spectrum Disorder [C] . Safae Cherdal, Salma Mouline International Conference on Sciences of Electronics, Technologies of Information and Telecommunications . 2016

机译：Petri网模型，用于模拟和分析自闭症谱系障碍中的叶酸缺乏和高同型半胱氨酸血症
5. The modulatory effects of folate deficiency on mRNA and/or protein expression of the genes involved in folate metabolism and one-carbon transfer reactions using an in vitro folate deficient model of colorectal cancer. [D] . Hayashi, Inki. 2005

机译：使用体外结直肠癌的叶酸缺乏模型，叶酸缺乏对参与叶酸代谢和单碳转移反应的基因的mRNA和/或蛋白质表达的调节作用。
6. Unusual association of diseases/symptoms: Severe folate-deficiency pancytopenia [O] . Viktoriya Clarke, Simon Weston-Smith 2010

机译：异常的疾病/症状关联：严重的叶酸缺乏全血细胞减少症
7. Severe pancytopenia due to acute folate deficiency despite normal folate erythrocyte level [O] . Antoine Huguenin, Sara Barraud, Sylvie Daliphard, 2016

机译：尽管正常的叶酸红细胞水平，严重的植物特迟因急性叶酸缺乏症
8. Study of the Neurological Effects of Low Level Methanol in Normal Subjects andSubjects with Susceptibility to Folate Deficiency [R] . Osterloh, J. 1995

机译：低水平甲醇在正常人和叶酸缺乏易感人群中的神经学作用研究

Severe pancytopenia due to acute folate deficiency despite normal folate erythrocyte level

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