...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Assessment >Neurobehavioral Traits as Transdiagnostic Predictors of Clinical Problems
【24h】

Neurobehavioral Traits as Transdiagnostic Predictors of Clinical Problems

机译：神经行为特征作为临床问题的诊断诊断依据

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The National Institute of Mental Health Research Domain Criteria initiative (Insel et al., 2010) calls for a focus on biologically meaningful dimensional constructs in the study of clinical problems. Examples are needed of how Research Domain Criteria constructs can be linked to clinical problems. We examined how two such constructs, threat sensitivity (THT+) and weak inhibitory control (INH-), operationalized using scale measures of fear/fearlessness and inhibition/disinhibition dimensions from established structural models, predicted symptoms of multiple Diagnostic and Statistical Manual of Mental Disorders (4th edition) clinical disorders in 471 community adults. Robust relationships with internalizing disorder symptoms were evident for both trait variables, with THT+ more predictive of fear disorder symptoms and INH- more predictive of distress disorder symptoms. For substance-related problems, prediction was evident only for INH-. Additionally, interactive effects of THT+ and INH- were found for distress disorders, and to a lesser extent, fear disorders. Given their well-established physiological correlates, these dispositional variables represent prime targets for combined psychometric-neurophysiological assessment of broad liabilities to multiple forms of psychopathology.
机译：美国国家心理健康研究所研究领域标准倡议（Insel等，2010）呼吁在研究临床问题时关注生物学上有意义的维度构造。需要有关如何将“研究领域标准”构建体与临床问题联系起来的示例。我们研究了如何使用已建立的结构模型对恐惧/无畏和抑制/抑制的尺度测量来对两种这样的结构，即威胁敏感性（THT +）和弱抑制控制（INH-）进行操作，以及多种精神疾病诊断和统计手册的预测症状（第4版）471位社区成年人的临床疾病。两种性状变量均与内在失调症状具有牢固的关系，其中THT +更能预测恐惧症症状，而INH-更能预测苦恼症状。对于与物质有关的问题，只有INH-可以预测。另外，发现THT +和INH-的交互作用可缓解窘迫疾病，并在较小程度上缓解恐惧障碍。鉴于它们建立良好的生理相关性，这些处置变量代表了对多种形式的心理病理学广泛责任进行综合心理计量-神经生理学评估的主要目标。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号