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首页> 外文期刊>Brain injury: BI >Individual profiles of predictors and their relations to 10 years outcome after childhood traumatic brain injury
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Individual profiles of predictors and their relations to 10 years outcome after childhood traumatic brain injury

机译：儿童创伤性脑损伤后预测因子的个人资料及其与10年结局的关系

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Background: Outcome after childhood traumatic brain injury (CTBI) is heterogeneous, with several predictors influencing long-term outcome. Method: This exploratory study used person-oriented cluster analysis to investigate individual profiles of medical, psychological and social predictors and their relation to longitudinal development in a sample of 127 participants with mild, moderate and severe CTBI. Outcome of cognitive, adaptive and academic function was measured at 30 months and 10 years post-injury. Results: A nine-cluster solution, explaining 67% of the variance in the sample, resulted in two clusters with individuals with mostly mild injuries, five with mostly moderate injured individuals and two clusters with severely injured individuals. Best outcome at 10 years post-injury had a cluster with individuals with moderate injuries, young age at injury, average socioeconomic status (SES) and high pre-injury adaptive function. Worst outcome had a small cluster with severely injured individuals, young age at injury, average SES and average pre-injury adaptive function. Conclusions: The findings suggest that pre-injury adaptive function is an influential predictor of outcome following moderate CTBI. Age at injury in the severe group appears to have increased influence over time, with younger age at injury associated with reduced outcome at 10 years after severe CTBI.
机译：背景：儿童创伤性脑损伤（CTBI）后的结果是异质的，有几种预测因素会影响长期结果。方法：这项探索性研究使用了以人为本的聚类分析，调查了127名轻度，中度和重度CTBI参与者的医学，心理和社会预测因素的个人概况及其与纵向发展的关系。在损伤后30个月和10年测量认知，适应和学术功能的结果。结果：九簇解决方案解释了样本中67％的方差，结果导致两个簇的个体受轻度伤害，大多数五个群体受中度伤害，而另外两个簇则受严重伤害。损伤后10年的最佳结局是中度受伤，受伤年轻，平均社会经济状况（SES）和高损伤前适应功能的个体。结局最差的是一小群，其中有严重受伤的个体，受伤年龄，平均SES和平均损伤前适应功能。结论：研究结果表明，中度CTBI后损伤前适应功能是影响预后的重要指标。严重组的受伤年龄似乎随着时间的推移而增加，严重的CTBI后10年，受伤年龄越小，预后降低。

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