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首页> 外文期刊>Brain injury: BI >Community versus orthopaedic controls in traumatic brain injury research: How comparable are they?
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Community versus orthopaedic controls in traumatic brain injury research: How comparable are they?

机译：创伤性脑损伤研究中的社区控制与骨科控制：它们的可比性如何？

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Background: Community (CC) or orthopaedic/injury (OC) control groups are typically used to evaluate the consequences of traumatic brain injuries (TBIs). Whereas CCs match for demographic variables and are readily available, OCs may additionally control for other pre-and post-injury variables but are more costly to recruit. Together, they enable an evaluation of brain-vs general-injury effects. However, the comparability of these two groups and the increase in control over confounding variables when OCs are used has rarely been examined. Method: The current study compared samples of CCs (n=71) and OCs (n=69), aged between 18-80, on a range of demographic (age, gender, education, socio-economic status), background (medical history, handedness), psychosocial (alcohol use, fatigue, pain, depression, social support, community integration, 'post-concussion' symptoms) and cognitive (motor and processing speed, memory, intellectual ability) variables. Results: The two groups were comparable on all variables, except alcohol use, with the OC group having higher levels of alcohol consumption. However, alcohol use did not correlate with any other variable, including commonly used measures of outcome following TBI. Conclusion: The current findings suggest that an orthopaedic injury control group does not have any clear advantages over a carefully recruited community control group.
机译：背景：社区（CC）或骨科/伤害（OC）对照组通常用于评估颅脑外伤（TBI）的后果。尽管CC可以匹配人口统计变量并且很容易获得，但OC可以额外控制其他伤害前后的变量，但招募成本更高。在一起，它们可以评估大脑与一般伤害的影响。但是，很少研究这两个组的可比性以及使用OC时对混杂变量的控制增加。方法：本研究比较了年龄在18-80岁之间的CCs（n = 71）和OCs（n = 69）样本，这些样本包括一系列人口统计数据（年龄，性别，教育程度，社会经济状况），背景（病史） ，惯用性），社会心理（饮酒，疲劳，疼痛，抑郁，社会支持，社区融合，“脑震荡后”症状）和认知（运动和加工速度，记忆力，智力）变量。结果：除酒精使用外，两组在所有变量上均具有可比性，OC组的酒精消耗量较高。但是，饮酒与其他任何变量均不相关，包括TBI后常用的结局指标。结论：目前的发现表明，骨科损伤对照组比精心招募的社区对照组没有明显优势。

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