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Ménière's disease: Is it time to approach it from another point of view?

机译:梅尼埃氏病:是时候从另一个角度来对待它了吗?

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Since it was first described in the 19th century, Meniere's disease (MD) has presented with a series of fundamental aspects the basis of which still remain unclear. It is commonly accepted that an endolym-phatic hydrops occurs; the modalities and mostly the causes of this alteration are still under debate despite numerous attempts at an explanation over the decades. A review of the suggested aetiopathogenetic explanations (1) reveals that these range from genetic abnormalities to viral infections, autoimmune alterations, Eustachian tube dysfunction, disorders of the transport and regulation of water, dietary factors, hormonal changes and psychological triggers. As a consequence of the uncertainties concerning MD, various medical and surgical therapeutic strategies have been proposed but none has proved universally acceptable to date.
机译:自19世纪首次描述以来,美尼尔氏病(MD)呈现出一系列基本方面,其基础仍不清楚。普遍认为发生内吞性水肿。尽管数十年来进行了许多尝试,但这种改变的方式和主要原因仍在争论中。对所建议的病原学解释的回顾(1)显示,这些疾病的范围从遗传异常到病毒感染,自身免疫改变,咽鼓管功能障碍,水的运输和调节紊乱,饮食因素,激素变化和心理触发因素。由于关于MD的不确定性,已经提出了各种医学和外科治疗策略,但是迄今为止没有一种被证明是普遍可接受的。

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