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首页> 外文期刊>Biomedical Engineering: Applications, Basis and Communications >PROSTATE DISEASES DIAGNOSIS IN POWER DOPPLER SONOGRAPHY
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PROSTATE DISEASES DIAGNOSIS IN POWER DOPPLER SONOGRAPHY

机译：多普勒超声对前列腺疾病的诊断

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摘要

In order to detect early prostate cancer, physicians usually apply the ultrasound imaging to visualize prostate for diagnosis. However, the traditional gray-scale ultrasound images that obtained from transrectal ultrasound of the prostate are often limited in diagnosing prostate cancer because of cancer heterogeneity, which makes direct diagnosing on the image difficult. Power Doppler ultrasound images improve the diagnosis by providing extra information of blood flow. Previous study has shown that increased blood inflow exists in prostate cancer. It is not difficult to differentiate the malignancy from benign prostate diseases by inspecting Doppler spectrum at bilateral neurovascular bundle sites and using resistive index. Although it is effective, however, it is hand-held, time-consuming, and only limited in a small and static region, which might not represent the real status of the whole prostate. Therefore, this study proposed an integrated dynamic approach to estimate the resistive index of blood flow in regions of interest within or all over the whole prostate. Merits of the proposed approach include the follows: resistive index can be calculated in serial prostate frames; the calculation can be performed on integral prostate region; and the proposed approach shortened the time needed to complete the calculation on whole prostate. Experimental results show that dynamic resistive index is better than conventional resistive index, and comparable with Prostate specific antigen (PSA) test in diagnosing prostate cancer, indicating high performance of the proposed approach, which also reveals feasibility and effectively of it.
机译：为了检测早期前列腺癌，医师通常应用超声成像使前列腺可视化以进行诊断。然而，由于癌症的异质性，从前列腺的经直肠超声获得的传统的灰度超声图像通常在诊断前列腺癌方面受到限制，这使得难以直接在图像上进行诊断。功率多普勒超声图像通过提供额外的血流信息来改善诊断。先前的研究表明，前列腺癌中血液流入增加。通过检查双侧神经血管束部位的多普勒频谱并使用电阻指数来区分恶性肿瘤与前列腺良性疾病并不困难。尽管它是有效的，但是它是手持式的，耗时的，并且仅限于小的静态区域，这可能并不代表整个前列腺的真实状态。因此，这项研究提出了一种综合的动态方法来估计整个前列腺内或整个前列腺内感兴趣区域的血流阻力指数。所提出的方法的优点包括：可以在一系列前列腺帧中计算电阻指数;可以在前列腺整体区域进行计算;所提出的方法缩短了完成整个前列腺的计算所需的时间。实验结果表明，动态电阻指数优于常规电阻指数，在前列腺癌的诊断中可与前列腺特异性抗原（PSA）测试相媲美，表明该方法具有较高的实用性，也证明了该方法的可行性和有效性。

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