B cell immunobiology in disease: evolving concepts from the clinic.

Martin F; Chan AC

首页> 外文期刊>Annual Review of Immunology >B cell immunobiology in disease: evolving concepts from the clinic.

【24h】

B cell immunobiology in disease: evolving concepts from the clinic.

机译：疾病中的B细胞免疫生物学：临床上不断发展的观念。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The pathogenic roles of B cells in autoimmune diseases occur through several mechanistic pathways that include autoantibodies, immune complexes, dendritic and T cell activation, cytokine synthesis, chemokine-mediated functions, and ectopic neolymphogenesis. Each of these pathways participate to different degrees in autoimmune diseases. The use of B cell-targeted and B cell subset-targeted therapies in humans is illuminating the mechanisms at work in a variety of human autoimmune diseases. In this review, we highlight some of these recent findings that provide insights into both murine models of autoimmunity and human autoimmune diseases.

机译：B细胞在自身免疫性疾病中的致病作用通过多种机制途径发生，包括自身抗体，免疫复合物，树突和T细胞活化，细胞因子合成，趋化因子介导的功能和异位新淋巴管生成。这些途径中的每一种都以不同程度参与自身免疫性疾病。在人类中使用以B细胞为靶标和以B细胞亚群为靶标的疗法正在阐明各种人类自身免疫性疾病的工作机制。在这篇综述中，我们重点介绍了这些最新发现中的一些，这些发现提供了对小鼠自身免疫性疾病模型和人类自身免疫性疾病模型的见识。

著录项

来源
《Annual Review of Immunology》 |2006年第0期|共30页
作者
Martin F; Chan AC;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
B-Lymphocytes; Autoimmune Diseases; Clinic; Human; B淋巴细胞; 自身免疫疾病;

机译：B-Lymphocytes;Autoimmune Diseases;Clinic;Human;B淋巴细胞;自身免疫疾病;

相似文献

外文文献
中文文献
专利

1. B cell immunobiology in disease: evolving concepts from the clinic. [J] . Martin F, Chan AC Annual Review of Immunology . 2006,第0期

机译：疾病中的B细胞免疫生物学：临床上不断发展的观念。
2. Graft-versus-host disease after allogeneic stem cell transplantation: evolving concepts and novel therapies including photopheresis. [J] . Komanduri KV, Couriel D, Champlin RE Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2006,第1Suppla2期

机译：同种异体干细胞移植后的移植物抗宿主病：不断发展的概念和包括光穿刺术在内的新疗法。
3. Cell therapy for multiple sclerosis: An evolving concept with implications for other neurodegenerative diseases [J] . RiceC.M., KempK., WilkinsA., The Lancet . 2013,第9899期

机译：多发性硬化症的细胞疗法：一种不断发展的概念，具有对其他神经变性疾病的影响
4. The Immunobiology of Regulatory T Cells in Hepatitis B and C [C] . Tri Nugraha Susilawati, Alfin Titian Permata, Sigit Setyawan International Conference on Science, Mathematics, Environment, and Education . 2019

机译：乙型肝炎中调节性T细胞的免疫学和C.
5. STUDIES IN CANINE IMMUNOBIOLOGY WITH SPECIAL REFERENCE TO MECHANISMS OF LYMPHOID CELL DEPLETION IN VIRAL DISEASE. [D] . JACOBY, ROBERT OTTINGER. 1969

机译：犬免疫生物学研究，特别涉及病毒性疾病中淋巴细胞耗竭的机制。
6. Rheumatoid Arthritis is a Lining Cell Disease: An Evolving Concept [O] . Leo BA van de Putte, PLEM van Lent, RJT Rodenburg, 2000

机译：类风湿关节炎是一种衬里细胞疾病：不断发展的概念。
7. Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation: Evolving Concepts and Novel Therapies Including Photopheresis [O] . Komanduri Krishna V., Couriel Daniel, Champlin Richard E. 2006

机译：同种异体干细胞移植后的移植物抗宿主病：不断发展的概念和包括光穿刺术在内的新疗法

B cell immunobiology in disease: evolving concepts from the clinic.

摘要

著录项

相似文献

相关主题

期刊订阅