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首页> 外文期刊>Indian Journal of Small Ruminants >Bilateral mixed bacterial pyelonephritis in a crossbred sheep.
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Bilateral mixed bacterial pyelonephritis in a crossbred sheep.

机译：杂交绵羊双侧混合细菌性肾盂肾炎。

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摘要

Necropsy of a weaner, crossbred male sheep was performed having a clinical history of anorexia and weakness. The main finding revealed severe bilateral pyelonephritis. The right kidney was highly enlarged with patchy congestion, ruptured surface and haemorrhage. The renal pelvis and calyces were highly dilated with purulent content on sagittal section. The left kidney also had almost similar lesions. On bacteriological investigation Corynebacterium pseudotuberculosis, C. renale and Proteus spp. were isolated. C. pseudotuberculosis was further confirmed by polymerase chain reaction (PCR), which yielded 551 bp and 382 bp amplified products of proline iminopeptidase (PIP), and nicotinamide adenine dinucleotide phosphate (NADP) oxidoreductase, respectively. Histopathologically, lesions were most severe in the medullary regions. The tubular lumen was dilated with densely eosinophilic casts. The glomeruli were less affected in comparison to the tubules. The interstitial tissues were infiltrated with lymphocytes and plasma cells. The renal pelvis was infiltrated with neutrophils.
机译：对断奶的杂种公羊进行尸检，其临床病史为厌食和虚弱。主要发现显示严重的双侧肾盂肾炎。右肾高度肿大，有斑块状充血，表面破裂和出血。肾盂和肾盏高度扩张，矢状切面有脓性成分。左肾也有几乎相似的病变。在细菌学调查中，假结核棒杆菌，肾形念珠菌和变形杆菌属。被隔离了。通过聚合酶链反应（PCR）进一步证实了假结核杆菌。该酶分别产生了551 bp和382 bp的脯氨酸亚肽酶（PIP）和烟酰胺腺嘌呤二核苷酸磷酸（NADP）氧化还原酶扩增产物。在组织病理学上，病变在髓质区域最严重。肾小管腔用嗜酸性粒细胞扩张。与肾小管相比，肾小球受到的影响较小。淋巴细胞和浆细胞浸润了间质组织。肾盂被中性粒细胞浸润。

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