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首页> 外文期刊>Indian Journal of Small Ruminants >Sex chromosome chimerism (60, XX/XY) and sister chromatid exchange frequency variation in a hermaphrodite goat.
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Sex chromosome chimerism (60, XX/XY) and sister chromatid exchange frequency variation in a hermaphrodite goat.

机译：雌雄同体山羊的性染色体嵌合（60，XX / XY）和姐妹染色单体交换频率变化。

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摘要

Association of a variety of different chromosome abnormalities with disturbed fertility is widely observed in various mammalian species. The present study was carried out in a one year old goat with abnormal external reproductive organs to ascertain the chromosomal complement and the mean sister chromatid exchange (SCE). Blood sample was collected in heparinised vacutainer from a kid exhibiting narrow vulval opening with a hypertrophic clitoris and a small scrotal sac. Short-term leucocyte culture was carried out to examine the metaphase spreads and ascertain the chromosome complement. On examination of the metaphase spreads under 1000x magnification, chromosome complement of 60, XX/XY was observed. A significant increase in the mean SCE frequency of 13.00+or-0.06 (6-15) was observed when compared to 5.22+or-0.10 (3-11) in normal two goats born as co-triplet to the affected goat.
机译：在各种哺乳动物中广泛观察到各种不同染色体异常与受精能力的关联。本研究是在具有外部生殖器官异常的一岁山羊中进行的，以确定染色体补体和平均姐妹染色单体交换（SCE）。在一个肝素化的真空容器中，从一个狭窄的外阴开口，肥厚的阴蒂和一个小阴囊囊中收集血样。进行短期白细胞培养以检查中期扩散并确定染色体补体。在1000x放大倍数下检查中期扩散，观察到60，XX / XY的染色体补体。在正常的两只作为患病山羊的三胞胎共同出生的山羊中，与5.22+或-0.10（3-11）相比，观察到平均SCE频率显着增加了13.00+或-0.06（6-15）。

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