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首页> 外文期刊>Indian journal of physiology and pharmacology >ASSOCIATION OF PATTERN REVERSAL VEP PARAMETERS WITH THE MEANDEFECT OF HUMPHREY VISUAL FIELD IN PATIENTS OF PRIMARY OPEN ANGLEGLAUCOMA
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ASSOCIATION OF PATTERN REVERSAL VEP PARAMETERS WITH THE MEANDEFECT OF HUMPHREY VISUAL FIELD IN PATIENTS OF PRIMARY OPEN ANGLEGLAUCOMA

机译：原发性开角型青光眼患者模式逆向VEP参数与汉普视视野的关联

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Glaucoma is a chronic, progressive bilateral optic neuropathy which disturbs the structural or functional integrity of the optic nerve that causes characteristic atrophic changes in it, which leads to specific visual field defects over time with loss of visual function. Primary open angle glaucoma (POAG) is the most common form of glaucoma in India and is fast emerging as a major cause of bilateral blindness. This rural hospital based study was conducted to evaluate whether glaucomatous visual field defects particularly the mean defect of Humphrey visual field could be related to VEP parameters of patients having POAG. Visual field by Humphrey perimeter and simultaneous recordings of pattern reversal visual evoked potential (PRVEP) were assessed in 100 patients with POAG. There was a significant (P<0.05) negative correlation of P100 latency, N155 latency and P100 duration and a highly significant (P<0.001) positive correlation of P100 amplitude with mean deviation (index of global visual field damage, MD) of Humphrey-visual field in the subjects of POAG in various age groups. N70 latency showed a non-significant positive correlation with MD. The VEP changes observed by us in POAG patients were consistent with the progressing mean defect quantitatively. Therefore, it can be concluded that the VEP parameters can be useful quantitative indices in the evaluation of glaucomatous visual function damage.
机译：青光眼是一种慢性进行性双侧视神经病变，会干扰视神经的结构或功能完整性，从而引起视神经萎缩性变化，从而导致特定的视野缺损，并随着时间的推移丧失视功能。原发性开角型青光眼（POAG）是印度最常见的青光眼形式，并且正在迅速发展为双眼失明的主要原因。这项基于农村医院的研究旨在评估青光眼视野缺损，特别是汉弗莱视野的平均缺损是否与POAG患者的VEP参数有关。通过Humphrey视野观察视野，并同时记录100例POAG患者的模式反转视觉诱发电位（PRVEP）。 P100潜伏期，N155潜伏期和P100持续时间呈显着（P <0.05）负相关，而P100振幅与汉弗莱-的平均偏差（全球视野损害指数，MD）呈高度显着（P <0.001）正相关。各个年龄段的POAG受试者的视野。 N70潜伏期显示与MD无显着正相关。我们在POAG患者中观察到的VEP变化在数量上与进展中的平均缺陷相一致。因此，可以得出结论，VEP参数可以作为评估青光眼视觉功能损害的有用定量指标。

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