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Helicobacter pylori Seroprevalence in Selected Groups of Albanian Volunteers.

机译:阿尔巴尼亚志愿人员特定群体中的幽门螺杆菌血清阳性率。

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BACKGROUND: : Albania is a Mediterranean, South-East European developing country where epidemiological data on infectious diseases are scarce. In this study, the seroprevalence of Helicobacter pylori infection in 1,088 Albanian healthy volunteers (472 females followed-up to a prenatal clinic, 173 recruits, 443 health care workers) was evaluated. MATERIALS AND METHODS: : Sera were tested for immunoglobulin-G (IgG) antibodies against H. pylori using a quantitative enzyme immunosorbent assay. RESULTS: : The overall H. pylori seroprevalence was 70.7%. The H. pylori seroprevalence increased by age, from 60.4% in individuals younger than 20 years to 81% among those double dagger 50 years of age with a significant trend of increase by age. The overall seroprevalence was 73.9% for females and 59.5% for males. In addition the seroprevalence was 55.3% for people living in rural areas and 72.3% for people living in urban areas. No significant differences were found according to level of education except for individuals with elementary level of education. Nurses and hospital auxiliaries have significantly higher H. pylori seroprevalence when compared to other health care workers (physicians and office workers). When each variable (age, gender, area of residence, occupation, and education level) was adjusted for the confounding effect of the other variables by stepwise logistic analysis, we observed that age greater than 40 years and female gender remain the only variables independently associated with the presence of H. pylori IgG antibodies. CONCLUSIONS: : H. pylori is highly prevalent among the Albanian population. Improving living conditions, education in hygiene, and the supply of running water are measures to prevent the transmission of H. pylori infection and other infections spread by the fecal-oral route in Albania.
机译:背景:阿尔巴尼亚是地中海东南部的发展中国家,那里缺乏有关传染病的流行病学数据。在这项研究中,评估了1,088名阿尔巴尼亚健康志愿者(472名女性进入产前诊所,173名新兵,443名医护人员)中幽门螺杆菌感染的血清阳性率。材料和方法:使用定量酶免疫吸附测定法检测血清中针对幽门螺杆菌的免疫球蛋白-G(IgG)抗体。结果::幽门螺杆菌的总体血清阳性率为70.7%。幽门螺杆菌血清阳性率随年龄增加而增加,从20岁以下的个体的60.4%上升到50岁的双匕首的81%,并且有明显的年龄增长趋势。总体血清阳性率女性为73.9%,男性为59.5%。另外,农村地区和城市地区的血清阳性率分别为55.3%和72.3%。除了受过基本教育的人外,根据受教育程度没有发现显着差异。与其他卫生保健工作者(医师和办公室工作人员)相比,护士和医院辅助人员的幽门螺杆菌血清阳性率高得多。当通过逐步逻辑分析对每个变量(年龄,性别,居住地区,职业和教育水平)进行调整以适应其他变量的混杂影响时,我们观察到年龄大于40岁且女性仍然是唯一独立相关的变量幽门螺杆菌IgG抗体的存在。结论:幽门螺杆菌在阿尔巴尼亚族人群中高度流行。改善生活条件,进行卫生教育和提供自来水是防止幽门螺杆菌感染和阿尔巴尼亚粪便经口传播的其他感染的传播措施。

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