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Incidence of surgical site infections in general surgery in Italy.

机译:在意大利,一般外科手术中手术部位感染的发生率。

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BACKGROUND: Epidemiological study to determine surgical site infection (SSI) rates in surgical patients in Italy using the National Nosocomial Infections Surveillance system (NNIS), to monitor current surgical antimicrobial prophylaxis, and to identify possible modifiable risk factors for SSI. MATERIALS AND METHODS: Thirty-two general surgeries participated in the study. Main criteria for site inclusion were: > 20 operations per week and amoxycillin/clavulanate among prophylactic options. Each patient operated from April 1st to May 30th 2002 was surveyed until 30 days after the operation. SSI cumulative incidence rates and 95% confidence intervals (95%CI) were calculated. RESULTS: During the study period, 3,066 surgical procedures were performed in 2,972 patients. A total of 158 SSI were diagnosed in 154 patients: 96 (62.3%) were at superficial incision, 23 (14.9%) were at deep incision and 35 (22.7%) were at organ-space site. Incidence of SSI every 100 operations was 5.2% (95% CI 4.4-6.0). Of the 2,437 operated patients with clean or elective clean/contaminated or contaminated surgical procedure, 2,105 (86.4%) received antimicrobial prophylaxis, mainly amoxicillin/clavulanate (28.3%) and ceftizoxime (11.4%). Pre-operative hospital stay >/= 48 h, diabetes, obesity, and HIV/AIDS infection were statistically significantly associated with increased risk of SSI. CONCLUSIONS: The SSI rates found are comparable with European studies and can be a benchmark for national incidence data and for inter- and intra-hospital SSI rate comparisons.
机译:背景:流行病学研究使用意大利国家医院感染监测系统(NNIS)来确定意大利手术患者的手术部位感染(SSI)率,以监测当前的手术抗菌药物预防情况,并确定可能的SSI风险因素。材料与方法:32位普通外科医师参加了这项研究。部位纳入的主要标准是:每周> 20次手术,阿莫西林/克拉维酸盐是预防措施。对2002年4月1日至5月30日手术的所有患者进行调查,直至手术后30天。计算了SSI累积发生率和95%置信区间(95%CI)。结果:在研究期间,对2,972例患者进行了3,066例外科手术。在154例患者中总共诊断出158例SSI:浅切切口96例(62.3%),深切口23例(14.9%),器官间隙35例(22.7%)。每100例SSI发生率为5.2%(95%CI 4.4-6.0)。在2437名接受过清洁或选择性清洁/污染或污染的外科手术患者中,有2105(86.4%)人接受了抗菌药物预防,主要是阿莫西林/克拉维酸盐(28.3%)和头孢唑肟(11.4%)。术前住院时间> / = 48小时,糖尿病,肥胖和HIV / AIDS感染与SSI风险增加在统计学上显着相关。结论:发现的SSI率与欧洲的研究相当,可以作为国家发病率数据以及医院间和院内SSI率比较的基准。

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