首页> 外文期刊>Infection >HIV-associated multicentric Castleman's disease after initiation of antiretroviral therapy: Experience of a European centre
【24h】

HIV-associated multicentric Castleman's disease after initiation of antiretroviral therapy: Experience of a European centre

机译:开始抗逆转录病毒治疗后,与艾滋病相关的多中心卡斯曼氏病:欧洲中心的经验

获取原文
获取原文并翻译 | 示例
           

摘要

Multicentric Castleman's disease (MCD) is a non-AIDS-defining lymphoproliferative disorder diagnosed with increased frequency in people infected with HIV [1-3]. Epidemiological studies have demonstrated no correlation with CD4 cell count or the use of antiretroviral therapy (ART) [1,2]. However, as early 1999, Zietz and colleagues reported a clustering of MCD cases in HIV-infected patients on highly active ART [4]. In our study, we analysed the temporal relationship between the initiation of ART and the occurrence of HIV-associated MCD (HIV-MCD) in 21 consecutive patients with HIV-MCD in a European HIV referral centre. We defined ART-associated HIV-MCD (in analogy with ART-associated cryptococco-sis) as a disease that occurs within 12 months of ART initiation, reintroduction or regimen switching after previous failure [5].
机译:多中心Castleman病(MCD)是一种非AIDS定义的淋巴组织增生性疾病,在HIV感染者中被诊断出频率增加[1-3]。流行病学研究表明与CD4细胞计数或使用抗逆转录病毒疗法(ART)无关[1,2]。然而,在1999年初,Zietz及其同事报道了在HIV感染患者中,在高度活跃的抗逆转录病毒治疗中发生了MCD病例聚类[4]。在我们的研究中,我们分析了欧洲艾滋病毒转诊中心连续21例HIV-MCD患者中ART起始与HIV相关MCD(HIV-MCD)发生之间的时间关系。我们将与ART相关的HIV-MCD(类似于与ART相关的隐球菌病)定义为在先前失败后于ART起始,重新引入或方案转换后12个月内发生的疾病[5]。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号