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首页> 外文期刊>British Journal of Haematology >Comment on Guidelines on oral anticoagulation with warfarin--4th edition.
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Comment on Guidelines on oral anticoagulation with warfarin--4th edition.

机译:使用华法林第4版评论《口服抗凝指南》。

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摘要

In response to the recently updated guidance for anticoagu-lation with warfarin (Keeling et al, 2011), we were disappointed to note that there was no consideration given to the issue of left ventricular thrombus and anticoagulation. This is a not uncommonly encountered scenario, and one for which little robust evidence exists to assist with the management.Left ventricular thrombus is commonly seen in the context of severely reduced ventricular function and low-flow states, and may occur in myocardial infarction or other non-ischaemic cardiomyopathy. Left ventricular thrombus may be asymptomatic and detected during investigations such as echocardiography or left ventriculography, or alternatively may give rise to cardio-embolic phenomena.Once detected, there is little available evidence to guide duration of therapy in this group of patients, and the decision becomes even more complex in ischaemic cardiomyopathy with coronary artery stenting when patients are already on antiplatelet therapy.
机译:为响应最近更新的与华法林抗凝的指南(Keeling等,2011),我们感到失望的是,我们没有考虑到左心室血栓和抗凝的问题。这是一种罕见的情况,很少有有力的证据可以帮助进行治疗。左室血栓通常出现在严重的心室功能降低和低流量状态的背景下,并可能发生在心肌梗塞或其他情况下。非缺血性心肌病。左心室血栓可能无症状并在超声心动图或左心室造影等检查过程中被发现,或者可能引起心脏栓塞现象。一旦发现,尚无可用的证据来指导此类患者的治疗时间,因此当患者已经接受抗血小板治疗时,在冠状动脉支架置入术治疗的缺血性心肌病中,情况变得更加复杂。

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