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首页> 外文期刊>Briefings in functional genomics & proteomics >Development and perspectives of scientific services offered by genomic biological resource centres
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Development and perspectives of scientific services offered by genomic biological resource centres

机译:基因组生物资源中心提供的科学服务的发展和前景

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摘要

A number of fundamental technical developments like the evolvement of oligonucleotide microarrays, new sequencing technologies and gene synthesis have considerably changed the character of genomic biological resource centres in recent years. While genomic biological resource centres traditionally served mainly as providers of sparsely characterized cDNA clones and clone sets, there is nowadays a clear tendency towards well-characterized, high-quality clones. In addition, major new service units like microarray services have developed, which are completely independent of clone collections, reflecting the co-evolution of data generation and technology development. The new technologies require an increasingly higher degree of specialization, data integration and quality standards. Altogether, these developments result in spin-offs of highly specialized biotech companies, some of which will take a prominent position in translational medicine.
机译:近年来,许多基础技术发展,例如寡核苷酸微阵列的发展,新的测序技术和基因合成,已大大改变了基因组生物资源中心的特征。传统上,基因组生物资源中心主要充当稀疏表征的cDNA克隆和克隆集的提供者,但如今,有一种明显的趋势,即倾向于特征明确的高质量克隆。此外,已经开发出了主要的新服务单元,例如微阵列服务,它们完全独立于克隆集合,反映了数据生成和技术开发的共同发展。新技术需要越来越高的专业化程度,数据集成和质量标准。总而言之,这些发展导致了高度专业化的生物技术公司的分拆,其中一些将在转化医学中占据重要地位。

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