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Chemotherapy of ovine coccidiosis

机译：绵羊球虫病的化学疗法

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Experimental infections were successfully established in lambs by inoculation of 4xl05 oocysts of mixed eimerian species comprising of E. ahsata, E. crandallis, E. intricata, E. ovina, E. ovinoidalis and E. parva for studying chemotherapeutic trials.Animals treated with sulphachloryrazine sodium at 0.12 g/kg body weight for 7 days had no clinical signs of coccidiosia, reduction in oocyst output (98.39 percent) and increased body weight gain whereas animals treated with maduramicin at Srng/kg body weight and control group animals had diarrhoea, no reduction in oocyst count and reduction in body weight. Haematological values like Hb, PCV, TEC in sulphachlorpyrazine sodium treated lambs were markedly reduced before treatment but returned to normal after 45 days post-treatment whereas in maduramicin treated and the control group lambs, the levels continued to be low.
机译：通过接种4x1005混合的艾美球虫卵囊成功地在羔羊中建立了实验性感染，这些混合的艾美球虫包括ahsata，E.crandallis，E.intricata，E.ovina，E.ovinoidalis和E.parva，用于研究化学疗法试验。钠在0.12 g / kg体重下持续7天没有球虫病的临床体征，卵囊产量减少（98.39％）且体重增加增加，而以Srng / kg体重用马杜霉素治疗的动物和对照组动物出现腹泻，没有减少卵囊计数和减轻体重。磺胺氯吡嗪钠处理的羔羊的血液学指标，如Hb，PCV，TEC均在治疗前显着降低，但在治疗后45天后恢复正常，而经马杜拉霉素和对照组的羔羊的血液学指标持续较低。

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