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首页> 外文期刊>International angiology: A journal of the International Union of Angiology >Trace elements and toxic heavy metals play a role in Buerger's disease and atherosclerotic peripheral arterial occlusive disease.
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Trace elements and toxic heavy metals play a role in Buerger's disease and atherosclerotic peripheral arterial occlusive disease.

机译:微量元素和有毒重金属在Buerger病和动脉粥样硬化性外周动脉闭塞性疾病中起作用。

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摘要

Arslan et at report the possible influence of trace elements and toxic heavy metals on disease process of Thromboangiitis Obliterans (TAG).I also would like to emphasize the possible role of lead (Pb) in pathophysiology of Buerger's disease based on five patients with the clinical features of Buerger s disease who reported to Emam reza hospital in northeastern Iran. Among the five cases, four were passive smokers and one chewed tobacco. The urine cotinine level of the patients measured very low or zero using a rapid semi-quantitative test, Smokescreen. However, all of them were opium addicts. Oral methadone was substituted for opium. Interestingly, after approximately a week, their burning pain diminished and other ischemic signs started to improve; and one patient with a 4-months chronic ulcer finally healed after methadone substitution (Figure 1). Poor ulcer healing had also been noticed in the patients who gave up smoking but continued to use opium.
机译:Arslan等人在报告中指出了微量元素和有毒重金属可能对闭塞性血栓性血管炎(TAG)疾病进程的影响。我还想根据五名临床患者强调铅(Pb)在Buerger病的病理生理中的可能作用。向伊朗东​​北部Emam reza医院报告的Buerger病的特征。在这五宗个案中,有四名是被动吸烟者,另一名是咀嚼烟草。使用快速的半定量测试烟屏测定患者的尿可替宁水平非常低或为零。但是,他们都是鸦片瘾君子。口服美沙酮代替了鸦片。有趣的是,大约一周后,他们的灼痛减轻了,其他缺血迹象开始改善。美沙酮替代后,一名患有4个月慢性溃疡的患者终于he愈(图1)。在戒烟但继续使用鸦片的患者中也发现溃疡愈合不佳。

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