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首页> 外文期刊>International Dairy Journal >Bile-resistant derivatives obtained from non-intestinal dairy lactobacilli
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Bile-resistant derivatives obtained from non-intestinal dairy lactobacilli

机译：从非肠道乳杆菌中获得的抗胆汁衍生物

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摘要

Our aim was to obtain derivatives of non-intestinal lactobacilli - commonly used in the dairy industry - able to grow under physiological concentrations of bile salts. Six resistant derivatives (five from Lactobacillus delbrueckii subsp. lactis and one from L. acidophilus) growing in the presence of 0.5% bile salts were obtained from 24 strains of L. delbrueckii subsp. bulgaricus, L. delbrueckii subsp. lactis and L. helveticus, and also one strain of L. acidophilus with low resistance to bile salts. Carbohydrate fermentation profiles remained unchanged but the rate of fermentation of several sugars was generally slower in bile-resistant derivatives. No significant differences with respect to the parent strains were observed for the cell-wall hydrophobicity, capacity to grow in milk and survival during frozen storage. Some bile-resistant derivatives were also resistant to low pH, but in other strains this capacity was acquired following progressive adaptation to low pH. Adaptation to bile salts and low pH might be valuable tools for increasing the survival under gastrointestinal conditions of non-intestinal lactobacilli used for the manufacture of dairy products.
机译：我们的目标是获得非肠道乳杆菌（通常用于乳业）的衍生物，该衍生物能够在生理浓度的胆汁盐下生长。从24株德氏乳杆菌亚种中获得了在0.5％的胆盐存在下生长的六种抗性衍生物（五种来自德氏乳杆菌乳酸菌亚种，一个来自嗜酸乳杆菌。）。保加利亚，德氏乳杆菌亚种。乳酸菌和瑞士乳杆菌，还有一株对胆汁盐抗性低的嗜酸乳杆菌。碳水化合物的发酵特性保持不变，但在抗胆汁的衍生物中，几种糖的发酵速率通常较慢。相对于亲本菌株，在细胞壁疏水性，在牛奶中生长的能力和冷冻保存期间的存活率方面没有观察到显着差异。一些抗胆汁的衍生物也对低pH具有抗性，但是在其他菌株中，这种能力是在逐渐适应低pH后获得的。适应胆汁盐和低pH值可能是增加胃肠道条件下用于生产乳制品的非肠道乳酸菌存活率的重要工具。

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