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首页> 外文期刊>International journal of antimicrobial agents >Streptococcus pneumoniae in Saudi Arabia: antibiotic resistance and serotypes of recent clinical isolates
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Streptococcus pneumoniae in Saudi Arabia: antibiotic resistance and serotypes of recent clinical isolates

机译：沙特阿拉伯的肺炎链球菌：近期临床分离株的抗生素耐药性和血清型

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During 2000, 154 clinical Streptococcus pneumoniae isolates were collected from or through three major hospitals serving the Western, Central, and Eastern regions of the Kingdom of Saudi Arabia. Ninety-one (59.1%) of the 154 isolates were resistant to penicillin with 23 strains (14.9%) highly resistant. Resistance was more prevalent among isolates obtained from patients <10 years of age and from isolates cultured from blood and cerebral spinal fluid. Decreased sensitivity to ceftriaxone, erythromycin, trimethoprim-sulphamethoxazole, and levofloxacin was found in 14.9, 15.6, 9.7, and 1.3% of isolates, respectively. There were no significant differences in the resistance pattern between isolates obtained from patients in the three different geographical areas. Serotypes of 116 isolates revealed the most prevalent types to be (descending order) 4, 3, 19F, 9V, 6A, 19A, 14 and 23F, comprising 75% of all strains typed; 9.5% of isolates were nontypable. S. pneumoniae isolates from Saudi Arabia have become more resistant to penicillin and other antimicrobials over the past 20 years. (C) 2003 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved. [References: 24]
机译：2000年期间，从或通过服务于沙特阿拉伯王国西部，中部和东部地区的三家主要医院收集了154株临床肺炎链球菌分离株。 154株菌株中有91株（59.1％）对青霉素有耐药性，其中23株（14.9％）具有高度耐药性。在<10岁患者以及从血液和脑脊髓液培养的分离株中分离出的分离株中，耐药性更为普遍。分别在14.9％，15.6％，9.7％和1.3％的分离物中发现对头孢曲松，红霉素，甲氧苄啶-磺胺甲恶唑和左氧氟沙星的敏感性降低。从三个不同地理区域的患者获得的分离株之间的耐药模式没有显着差异。 116种分离株的血清型显示最普遍的类型是（降序排列）4、3、19F，9V，6A，19A，14和23F，占所有分型菌株的75％。 9.5％的分离株不可分。在过去的20年中，来自沙特阿拉伯的肺炎链球菌分离株对青霉素和其他抗菌药的耐药性更高。 （C）2003年Elsevier B.V.和国际化学疗法学会。版权所有。 [参考：24]

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